Dimethyl Sulfate as Methylation Agent and Solvent in Highly Regioselective Synthesis of Methyl Salicylate Using Sodium Bicarbonate as a Base

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Main Authors: Milton de Souza Freitas, David Lee Nelson, João Victor G. de Sousa, Alexandre P. Wentz, Dayane B. Tada, Rafaela C. Queiroz, Carolina R. Hurtado, Erenilda F. de Macedo, Katia Conceição, Gabriela R. Hurtado, Fernando L. P. Pessoa, Yan Valdez S Rodrigues, Gabriel de P. Bueno, Giuliano C. Clososki, Sandro L. Barbosa
Format: Article
Language:English
Published: American Chemical Society 2025-03-01
Series:ACS Omega
Online Access:https://doi.org/10.1021/acsomega.4c10962
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author Milton de Souza Freitas
David Lee Nelson
João Victor G. de Sousa
Alexandre P. Wentz
Dayane B. Tada
Rafaela C. Queiroz
Carolina R. Hurtado
Erenilda F. de Macedo
Katia Conceição
Gabriela R. Hurtado
Fernando L. P. Pessoa
Yan Valdez S Rodrigues
Gabriel de P. Bueno
Giuliano C. Clososki
Sandro L. Barbosa
author_facet Milton de Souza Freitas
David Lee Nelson
João Victor G. de Sousa
Alexandre P. Wentz
Dayane B. Tada
Rafaela C. Queiroz
Carolina R. Hurtado
Erenilda F. de Macedo
Katia Conceição
Gabriela R. Hurtado
Fernando L. P. Pessoa
Yan Valdez S Rodrigues
Gabriel de P. Bueno
Giuliano C. Clososki
Sandro L. Barbosa
author_sort Milton de Souza Freitas
collection DOAJ
format Article
id doaj-art-ce5a0767de2b49f6a00a7072d61836db
institution OA Journals
issn 2470-1343
language English
publishDate 2025-03-01
publisher American Chemical Society
record_format Article
series ACS Omega
spelling doaj-art-ce5a0767de2b49f6a00a7072d61836db2025-08-20T02:26:02ZengAmerican Chemical SocietyACS Omega2470-13432025-03-011013132601326810.1021/acsomega.4c10962Dimethyl Sulfate as Methylation Agent and Solvent in Highly Regioselective Synthesis of Methyl Salicylate Using Sodium Bicarbonate as a BaseMilton de Souza Freitas0David Lee Nelson1João Victor G. de Sousa2Alexandre P. Wentz3Dayane B. Tada4Rafaela C. Queiroz5Carolina R. Hurtado6Erenilda F. de Macedo7Katia Conceição8Gabriela R. Hurtado9Fernando L. P. Pessoa10Yan Valdez S Rodrigues11Gabriel de P. Bueno12Giuliano C. Clososki13Sandro L. Barbosa14Department of Pharmacy, Universidade Federal dos Vales do Jequitinhonha e Mucuri-UFVJM, Diamantina, MG, BrazilDepartment of Pharmacy, Universidade Federal dos Vales do Jequitinhonha e Mucuri-UFVJM, Diamantina, MG, BrazilDepartment of Pharmacy, Universidade Federal dos Vales do Jequitinhonha e Mucuri-UFVJM, Diamantina, MG, BrazilDepartment of Pharmacy, Universidade Federal dos Vales do Jequitinhonha e Mucuri-UFVJM, Diamantina, MG, BrazilNanomaterials and Nanotoxicology Laboratory, Institute of Science and Technology, Federal University of São Paulo (UNIFESP), São José dos Campos, SP, BrazilNanomaterials and Nanotoxicology Laboratory, Institute of Science and Technology, Federal University of São Paulo (UNIFESP), São José dos Campos, SP, BrazilNanomaterials and Nanotoxicology Laboratory, Institute of Science and Technology, Federal University of São Paulo (UNIFESP), São José dos Campos, SP, BrazilNanomaterials and Nanotoxicology Laboratory, Institute of Science and Technology, Federal University of São Paulo (UNIFESP), São José dos Campos, SP, BrazilPeptide Biochemistry Laboratory, Institute of Science and Technology, Federal University of São Paulo (Unifesp), São José dos Campos, SP, BrazilInstitute of Science and Technology, São Paulo State University (UNESP), São José dos Campos, SP, BrazilCentro Universitário SENAI-CIMATEC, Salvador, BrazilCentro Universitário SENAI-CIMATEC, Salvador, BrazilResearch Center for Natural and Synthetic Products, Faculty of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto, SP, BrazilResearch Center for Natural and Synthetic Products, Faculty of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto, SP, BrazilDepartment of Pharmacy, Universidade Federal dos Vales do Jequitinhonha e Mucuri-UFVJM, Diamantina, MG, Brazilhttps://doi.org/10.1021/acsomega.4c10962
spellingShingle Milton de Souza Freitas
David Lee Nelson
João Victor G. de Sousa
Alexandre P. Wentz
Dayane B. Tada
Rafaela C. Queiroz
Carolina R. Hurtado
Erenilda F. de Macedo
Katia Conceição
Gabriela R. Hurtado
Fernando L. P. Pessoa
Yan Valdez S Rodrigues
Gabriel de P. Bueno
Giuliano C. Clososki
Sandro L. Barbosa
Dimethyl Sulfate as Methylation Agent and Solvent in Highly Regioselective Synthesis of Methyl Salicylate Using Sodium Bicarbonate as a Base
ACS Omega
title Dimethyl Sulfate as Methylation Agent and Solvent in Highly Regioselective Synthesis of Methyl Salicylate Using Sodium Bicarbonate as a Base
title_full Dimethyl Sulfate as Methylation Agent and Solvent in Highly Regioselective Synthesis of Methyl Salicylate Using Sodium Bicarbonate as a Base
title_fullStr Dimethyl Sulfate as Methylation Agent and Solvent in Highly Regioselective Synthesis of Methyl Salicylate Using Sodium Bicarbonate as a Base
title_full_unstemmed Dimethyl Sulfate as Methylation Agent and Solvent in Highly Regioselective Synthesis of Methyl Salicylate Using Sodium Bicarbonate as a Base
title_short Dimethyl Sulfate as Methylation Agent and Solvent in Highly Regioselective Synthesis of Methyl Salicylate Using Sodium Bicarbonate as a Base
title_sort dimethyl sulfate as methylation agent and solvent in highly regioselective synthesis of methyl salicylate using sodium bicarbonate as a base
url https://doi.org/10.1021/acsomega.4c10962
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