Potential Application of Tregitopes as Immunomodulating Agents in Multiple Sclerosis
The induction of immunologic tolerance is an important clinical goal in autoimmunity. CD4+ regulatory T (Treg) cells, defined by the expression of the transcription factor forkhead box P3 (FoxP3), play a central role in the control of autoimmune responses. Quantitative and qualitative defects of Tre...
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Main Authors: | Wassim Elyaman, Samia J. Khoury, David W. Scott, Anne S. De Groot |
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Format: | Article |
Language: | English |
Published: |
Wiley
2011-01-01
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Series: | Neurology Research International |
Online Access: | http://dx.doi.org/10.1155/2011/256460 |
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