Neutrophil-to-Lymphocyte Ratio Predicts Early Mortality in Patients with HBV-Related Decompensated Cirrhosis
Background. The neutrophil-to-lymphocyte ratio (NLR) is an inflammation index that has been shown to independently predict poor clinical outcomes. We aimed to evaluate the clinical value of NLR in the prediction of 30-day mortality in patients with HBV-related decompensated cirrhosis (HBV-DeCi). Met...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2016/4394650 |
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| author | Honggang Zhang Qinqin Sun Weilin Mao Jian Fan Bo Ye |
| author_facet | Honggang Zhang Qinqin Sun Weilin Mao Jian Fan Bo Ye |
| author_sort | Honggang Zhang |
| collection | DOAJ |
| description | Background. The neutrophil-to-lymphocyte ratio (NLR) is an inflammation index that has been shown to independently predict poor clinical outcomes. We aimed to evaluate the clinical value of NLR in the prediction of 30-day mortality in patients with HBV-related decompensated cirrhosis (HBV-DeCi). Methods. This was a retrospective cohort study that included 148 patients with HBV-DeCi. Results. An elevated NLR was associated with increased severity of liver disease and mortality within 30 days. Multivariate analysis suggested that NLR, similar to the model for end-stage liver disease (MELD) score, is an additional independent predictor of 30-day mortality (P<0.01). Conclusion. Our results suggest that a high NLR can be considered a new independent biomarker for predicting 30-day mortality in patients with HBV-DeCi. |
| format | Article |
| id | doaj-art-ce19d3d0fa5d40b2a608c8b0ca60ee8a |
| institution | OA Journals |
| issn | 1687-6121 1687-630X |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Gastroenterology Research and Practice |
| spelling | doaj-art-ce19d3d0fa5d40b2a608c8b0ca60ee8a2025-08-20T02:20:01ZengWileyGastroenterology Research and Practice1687-61211687-630X2016-01-01201610.1155/2016/43946504394650Neutrophil-to-Lymphocyte Ratio Predicts Early Mortality in Patients with HBV-Related Decompensated CirrhosisHonggang Zhang0Qinqin Sun1Weilin Mao2Jian Fan3Bo Ye4Department of Anesthesiology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Zhejiang 310003, ChinaDepartment of Urology, The Sixth Affiliated Hospital of Xinjiang Medical University, Xinjiang 830001, ChinaDepartment of Clinical Laboratory, The First Affiliated Hospital, College of Medicine, Zhejiang University, Zhejiang 310003, ChinaDepartment of Clinical Laboratory, The First Affiliated Hospital, College of Medicine, Zhejiang University, Zhejiang 310003, ChinaDepartment of Clinical Laboratory, The First Affiliated Hospital, College of Medicine, Zhejiang University, Zhejiang 310003, ChinaBackground. The neutrophil-to-lymphocyte ratio (NLR) is an inflammation index that has been shown to independently predict poor clinical outcomes. We aimed to evaluate the clinical value of NLR in the prediction of 30-day mortality in patients with HBV-related decompensated cirrhosis (HBV-DeCi). Methods. This was a retrospective cohort study that included 148 patients with HBV-DeCi. Results. An elevated NLR was associated with increased severity of liver disease and mortality within 30 days. Multivariate analysis suggested that NLR, similar to the model for end-stage liver disease (MELD) score, is an additional independent predictor of 30-day mortality (P<0.01). Conclusion. Our results suggest that a high NLR can be considered a new independent biomarker for predicting 30-day mortality in patients with HBV-DeCi.http://dx.doi.org/10.1155/2016/4394650 |
| spellingShingle | Honggang Zhang Qinqin Sun Weilin Mao Jian Fan Bo Ye Neutrophil-to-Lymphocyte Ratio Predicts Early Mortality in Patients with HBV-Related Decompensated Cirrhosis Gastroenterology Research and Practice |
| title | Neutrophil-to-Lymphocyte Ratio Predicts Early Mortality in Patients with HBV-Related Decompensated Cirrhosis |
| title_full | Neutrophil-to-Lymphocyte Ratio Predicts Early Mortality in Patients with HBV-Related Decompensated Cirrhosis |
| title_fullStr | Neutrophil-to-Lymphocyte Ratio Predicts Early Mortality in Patients with HBV-Related Decompensated Cirrhosis |
| title_full_unstemmed | Neutrophil-to-Lymphocyte Ratio Predicts Early Mortality in Patients with HBV-Related Decompensated Cirrhosis |
| title_short | Neutrophil-to-Lymphocyte Ratio Predicts Early Mortality in Patients with HBV-Related Decompensated Cirrhosis |
| title_sort | neutrophil to lymphocyte ratio predicts early mortality in patients with hbv related decompensated cirrhosis |
| url | http://dx.doi.org/10.1155/2016/4394650 |
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