Socioeconomic position across the life course and falls among middle- and older-aged adults: protocol for a systematic review

Introduction Individuals experiencing disadvantaged socioeconomic positions (SEPs) may be at increased risk of falls during middle and older age, and these impacts of socioeconomic factors may vary according to the duration, timing and sequencing of exposures across the life course. However, there h...

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Main Authors: Stéphane Cullati, Anita van Zwieten, Catherine Sherrington, Fiona M Blyth, Saman Khalatbari-Soltani, Marcia R Franco, Frerik Smit
Format: Article
Language:English
Published: BMJ Publishing Group 2025-01-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/15/1/e087971.full
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author Stéphane Cullati
Anita van Zwieten
Catherine Sherrington
Fiona M Blyth
Saman Khalatbari-Soltani
Marcia R Franco
Frerik Smit
author_facet Stéphane Cullati
Anita van Zwieten
Catherine Sherrington
Fiona M Blyth
Saman Khalatbari-Soltani
Marcia R Franco
Frerik Smit
author_sort Stéphane Cullati
collection DOAJ
description Introduction Individuals experiencing disadvantaged socioeconomic positions (SEPs) may be at increased risk of falls during middle and older age, and these impacts of socioeconomic factors may vary according to the duration, timing and sequencing of exposures across the life course. However, there has not been a recent systematic review of this evidence. This study, therefore, aims to synthesise existing knowledge on the association between SEP across the life course and falls within middle- and older-aged adults.Methods and analysis We systematically searched for literature in three academic databases from database inception to 15 March 2024: MEDLINE (Ovid), Embase (Ovid) and PsycInfo (Ovid). The search strategy combined MeSH headings and search terms related to SEP, falls, middle- and older-aged adults and observational studies. Cohort, case-control and cross-sectional studies with mean or median participant age of >40 years, which report on the association between at least one socioeconomic indicator across the life course and one fall outcome and are published in peer-reviewed academic journals were included. No language or geographic restrictions were imposed. Titles and abstracts were screened by one reviewer with 20% of titles and abstracts also screened by a second reviewer. Two reviewers independently screened full texts. Data will be extracted using a standardised Excel template. Using a modified Quality in Prognosis Studies (QUIPS) tool, the risk of bias of included studies will be assessed by one reviewer with 20% of studies also independently appraised by a second reviewer. Meta-analyses will be conducted if sufficient homogeneity between studies permits. Otherwise, a narrative synthesis of results will be undertaken.Ethics and dissemination As this is a review of published literature, no ethics approval is required. Findings will be disseminated through a journal article publication, conference presentations and plain-text summaries for public accessibility.PROSPERO registration number CRD42024534813.
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spelling doaj-art-cdefd1fd64544e6da87d3b7aa2b6bd6f2025-01-23T10:45:09ZengBMJ Publishing GroupBMJ Open2044-60552025-01-0115110.1136/bmjopen-2024-087971Socioeconomic position across the life course and falls among middle- and older-aged adults: protocol for a systematic reviewStéphane Cullati0Anita van Zwieten1Catherine Sherrington2Fiona M Blyth3Saman Khalatbari-Soltani4Marcia R Franco5Frerik Smit65 Population Health Laboratory (#PopHealthLab), University of Fribourg, Fribourg, Switzerland1 The University of Sydney School of Public Health, Sydney, New South Wales, Australia3 Sydney Musculoskeletal Health, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia1 The University of Sydney School of Public Health, Sydney, New South Wales, Australia1 The University of Sydney School of Public Health, Sydney, New South Wales, Australia3 Sydney Musculoskeletal Health, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia1 The University of Sydney School of Public Health, Sydney, New South Wales, AustraliaIntroduction Individuals experiencing disadvantaged socioeconomic positions (SEPs) may be at increased risk of falls during middle and older age, and these impacts of socioeconomic factors may vary according to the duration, timing and sequencing of exposures across the life course. However, there has not been a recent systematic review of this evidence. This study, therefore, aims to synthesise existing knowledge on the association between SEP across the life course and falls within middle- and older-aged adults.Methods and analysis We systematically searched for literature in three academic databases from database inception to 15 March 2024: MEDLINE (Ovid), Embase (Ovid) and PsycInfo (Ovid). The search strategy combined MeSH headings and search terms related to SEP, falls, middle- and older-aged adults and observational studies. Cohort, case-control and cross-sectional studies with mean or median participant age of >40 years, which report on the association between at least one socioeconomic indicator across the life course and one fall outcome and are published in peer-reviewed academic journals were included. No language or geographic restrictions were imposed. Titles and abstracts were screened by one reviewer with 20% of titles and abstracts also screened by a second reviewer. Two reviewers independently screened full texts. Data will be extracted using a standardised Excel template. Using a modified Quality in Prognosis Studies (QUIPS) tool, the risk of bias of included studies will be assessed by one reviewer with 20% of studies also independently appraised by a second reviewer. Meta-analyses will be conducted if sufficient homogeneity between studies permits. Otherwise, a narrative synthesis of results will be undertaken.Ethics and dissemination As this is a review of published literature, no ethics approval is required. Findings will be disseminated through a journal article publication, conference presentations and plain-text summaries for public accessibility.PROSPERO registration number CRD42024534813.https://bmjopen.bmj.com/content/15/1/e087971.full
spellingShingle Stéphane Cullati
Anita van Zwieten
Catherine Sherrington
Fiona M Blyth
Saman Khalatbari-Soltani
Marcia R Franco
Frerik Smit
Socioeconomic position across the life course and falls among middle- and older-aged adults: protocol for a systematic review
BMJ Open
title Socioeconomic position across the life course and falls among middle- and older-aged adults: protocol for a systematic review
title_full Socioeconomic position across the life course and falls among middle- and older-aged adults: protocol for a systematic review
title_fullStr Socioeconomic position across the life course and falls among middle- and older-aged adults: protocol for a systematic review
title_full_unstemmed Socioeconomic position across the life course and falls among middle- and older-aged adults: protocol for a systematic review
title_short Socioeconomic position across the life course and falls among middle- and older-aged adults: protocol for a systematic review
title_sort socioeconomic position across the life course and falls among middle and older aged adults protocol for a systematic review
url https://bmjopen.bmj.com/content/15/1/e087971.full
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