Imaging Features in Pancreatic Neuroendocrine Tumor with Intraductal Growth and Venous Invasion: A Case Report and Literature Review

Pancreatic neuroendocrine tumors (PanNETs) are a rare type of pancreatic neoplasm. Pan- NETs with intraductal growth are considered extremely rare, and ductal involvement in NETs has been reported to correlate with aggressive clinical behavior. A 67-year-old male was referred to our hospital for...

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Main Authors: Yoon Kyung Jung, Hyun Jeong Park, Hye Won Hwang, Eun Sun Lee, Rae Rim Ryu
Format: Article
Language:English
Published: The Korean Society of Radiology 2025-05-01
Series:Journal of the Korean Society of Radiology
Subjects:
Online Access:https://doi.org/10.3348/jksr.2024.0064
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author Yoon Kyung Jung
Hyun Jeong Park
Hye Won Hwang
Eun Sun Lee
Rae Rim Ryu
author_facet Yoon Kyung Jung
Hyun Jeong Park
Hye Won Hwang
Eun Sun Lee
Rae Rim Ryu
author_sort Yoon Kyung Jung
collection DOAJ
description Pancreatic neuroendocrine tumors (PanNETs) are a rare type of pancreatic neoplasm. Pan- NETs with intraductal growth are considered extremely rare, and ductal involvement in NETs has been reported to correlate with aggressive clinical behavior. A 67-year-old male was referred to our hospital for further evaluation of a pancreatic tumor. Various imaging modalities, including ultrasonography, contrast-enhanced CT, MRI, and endoscopic ultrasonography (EUS), demonstrated a well-defined pancreatic mass in the head and body, primarily located within the main pancreatic duct with extension to the main portal vein. Histological diagnosis from an EUS-guided biopsy revealed a grade 3 well-differentiated NET. The patient was scheduled for surgery; however, multiple additional bone metastases were identified on 18F-fluorodeoxyglucose PET/CT. Although the presence of intraductal growth and portal vein invasion is uncommon in PanNETs, aggressive workup and treatment are essential in such cases.
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publisher The Korean Society of Radiology
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spelling doaj-art-cde072284d7c420996e5d94e9f6703952025-08-20T03:22:26ZengThe Korean Society of RadiologyJournal of the Korean Society of Radiology2951-08052025-05-01863438444https://doi.org/10.3348/jksr.2024.0064Imaging Features in Pancreatic Neuroendocrine Tumor with Intraductal Growth and Venous Invasion: A Case Report and Literature ReviewYoon Kyung JungHyun Jeong ParkHye Won HwangEun Sun LeeRae Rim RyuPancreatic neuroendocrine tumors (PanNETs) are a rare type of pancreatic neoplasm. Pan- NETs with intraductal growth are considered extremely rare, and ductal involvement in NETs has been reported to correlate with aggressive clinical behavior. A 67-year-old male was referred to our hospital for further evaluation of a pancreatic tumor. Various imaging modalities, including ultrasonography, contrast-enhanced CT, MRI, and endoscopic ultrasonography (EUS), demonstrated a well-defined pancreatic mass in the head and body, primarily located within the main pancreatic duct with extension to the main portal vein. Histological diagnosis from an EUS-guided biopsy revealed a grade 3 well-differentiated NET. The patient was scheduled for surgery; however, multiple additional bone metastases were identified on 18F-fluorodeoxyglucose PET/CT. Although the presence of intraductal growth and portal vein invasion is uncommon in PanNETs, aggressive workup and treatment are essential in such cases.https://doi.org/10.3348/jksr.2024.0064pancreatic neuroendocrine tumorintraductal tumormain pancreatic ductportal vein invasion
spellingShingle Yoon Kyung Jung
Hyun Jeong Park
Hye Won Hwang
Eun Sun Lee
Rae Rim Ryu
Imaging Features in Pancreatic Neuroendocrine Tumor with Intraductal Growth and Venous Invasion: A Case Report and Literature Review
Journal of the Korean Society of Radiology
pancreatic neuroendocrine tumor
intraductal tumor
main pancreatic duct
portal vein invasion
title Imaging Features in Pancreatic Neuroendocrine Tumor with Intraductal Growth and Venous Invasion: A Case Report and Literature Review
title_full Imaging Features in Pancreatic Neuroendocrine Tumor with Intraductal Growth and Venous Invasion: A Case Report and Literature Review
title_fullStr Imaging Features in Pancreatic Neuroendocrine Tumor with Intraductal Growth and Venous Invasion: A Case Report and Literature Review
title_full_unstemmed Imaging Features in Pancreatic Neuroendocrine Tumor with Intraductal Growth and Venous Invasion: A Case Report and Literature Review
title_short Imaging Features in Pancreatic Neuroendocrine Tumor with Intraductal Growth and Venous Invasion: A Case Report and Literature Review
title_sort imaging features in pancreatic neuroendocrine tumor with intraductal growth and venous invasion a case report and literature review
topic pancreatic neuroendocrine tumor
intraductal tumor
main pancreatic duct
portal vein invasion
url https://doi.org/10.3348/jksr.2024.0064
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AT eunsunlee imagingfeaturesinpancreaticneuroendocrinetumorwithintraductalgrowthandvenousinvasionacasereportandliteraturereview
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