Goat Genomic Resources: The Search for Genes Associated with Its Economic Traits
Goat plays a crucial role in human livelihoods, being a major source of meat, milk, fiber, and hides, particularly under adverse climatic conditions. The goat genomics related to the candidate gene approach is now being used to recognize molecular mechanisms that have different expressions of growth...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2020-01-01
|
| Series: | International Journal of Genomics |
| Online Access: | http://dx.doi.org/10.1155/2020/5940205 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832547181110755328 |
|---|---|
| author | A. M. A. M. Zonaed Siddiki Gous Miah Md. Sirazul Islam Mahadia Kumkum Meheadi Hasan Rumi Abdul Baten Mohammad Alamgir Hossain |
| author_facet | A. M. A. M. Zonaed Siddiki Gous Miah Md. Sirazul Islam Mahadia Kumkum Meheadi Hasan Rumi Abdul Baten Mohammad Alamgir Hossain |
| author_sort | A. M. A. M. Zonaed Siddiki |
| collection | DOAJ |
| description | Goat plays a crucial role in human livelihoods, being a major source of meat, milk, fiber, and hides, particularly under adverse climatic conditions. The goat genomics related to the candidate gene approach is now being used to recognize molecular mechanisms that have different expressions of growth, reproductive, milk, wool, and disease resistance. The appropriate literature on this topic has been reviewed in this article. Several genetic characterization attempts of different goats have reported the existence of genotypic and morphological variations between different goat populations. As a result, different whole-genome sequences along with annotated gene sequences, gene function, and other genomic information of different goats are available in different databases. The main objective of this review is to search the genes associated with economic traits in goats. More than 271 candidate genes have been discovered in goats. Candidate genes influence the physiological pathway, metabolism, and expression of phenotypes. These genes have different functions on economically important traits. Some genes have pleiotropic effect for expression of phenotypic traits. Hence, recognizing candidate genes and their mutations that cause variations in gene expression and phenotype of an economic trait can help breeders look for genetic markers for specific economic traits. The availability of reference whole-genome assembly of goats, annotated genes, and transcriptomics makes comparative genomics a useful tool for systemic genetic upgradation. Identification and characterization of trait-associated sequence variations and gene will provide powerful means to give positive influences for future goat breeding program. |
| format | Article |
| id | doaj-art-cdc9d3e4630d442f823e450d787ec98e |
| institution | Kabale University |
| issn | 2314-436X 2314-4378 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Genomics |
| spelling | doaj-art-cdc9d3e4630d442f823e450d787ec98e2025-02-03T06:45:48ZengWileyInternational Journal of Genomics2314-436X2314-43782020-01-01202010.1155/2020/59402055940205Goat Genomic Resources: The Search for Genes Associated with Its Economic TraitsA. M. A. M. Zonaed Siddiki0Gous Miah1Md. Sirazul Islam2Mahadia Kumkum3Meheadi Hasan Rumi4Abdul Baten5Mohammad Alamgir Hossain6Genomics Research Group, Faculty of Veterinary Medicine, Chattogram Veterinary and Animal Sciences University (CVASU), Chattogram 4225, BangladeshDepartment of Genetics and Animal Breeding, Faculty of Veterinary Medicine, Chattogram Veterinary and Animal Sciences University (CVASU), Chattogram 4225, BangladeshGenomics Research Group, Faculty of Veterinary Medicine, Chattogram Veterinary and Animal Sciences University (CVASU), Chattogram 4225, BangladeshHuman Biology-Principles of Health and Disease, Ludwig Maximilians University, Munich, GermanyGenomics Research Group, Faculty of Veterinary Medicine, Chattogram Veterinary and Animal Sciences University (CVASU), Chattogram 4225, BangladeshAgResearch, Palmerston North 4410, Private Bag 11008, New ZealandDepartment of Pathology and Parasitology, Faculty of Veterinary Medicine, Chattogram Veterinary and Animal Sciences University (CVASU), Chattogram 4225, BangladeshGoat plays a crucial role in human livelihoods, being a major source of meat, milk, fiber, and hides, particularly under adverse climatic conditions. The goat genomics related to the candidate gene approach is now being used to recognize molecular mechanisms that have different expressions of growth, reproductive, milk, wool, and disease resistance. The appropriate literature on this topic has been reviewed in this article. Several genetic characterization attempts of different goats have reported the existence of genotypic and morphological variations between different goat populations. As a result, different whole-genome sequences along with annotated gene sequences, gene function, and other genomic information of different goats are available in different databases. The main objective of this review is to search the genes associated with economic traits in goats. More than 271 candidate genes have been discovered in goats. Candidate genes influence the physiological pathway, metabolism, and expression of phenotypes. These genes have different functions on economically important traits. Some genes have pleiotropic effect for expression of phenotypic traits. Hence, recognizing candidate genes and their mutations that cause variations in gene expression and phenotype of an economic trait can help breeders look for genetic markers for specific economic traits. The availability of reference whole-genome assembly of goats, annotated genes, and transcriptomics makes comparative genomics a useful tool for systemic genetic upgradation. Identification and characterization of trait-associated sequence variations and gene will provide powerful means to give positive influences for future goat breeding program.http://dx.doi.org/10.1155/2020/5940205 |
| spellingShingle | A. M. A. M. Zonaed Siddiki Gous Miah Md. Sirazul Islam Mahadia Kumkum Meheadi Hasan Rumi Abdul Baten Mohammad Alamgir Hossain Goat Genomic Resources: The Search for Genes Associated with Its Economic Traits International Journal of Genomics |
| title | Goat Genomic Resources: The Search for Genes Associated with Its Economic Traits |
| title_full | Goat Genomic Resources: The Search for Genes Associated with Its Economic Traits |
| title_fullStr | Goat Genomic Resources: The Search for Genes Associated with Its Economic Traits |
| title_full_unstemmed | Goat Genomic Resources: The Search for Genes Associated with Its Economic Traits |
| title_short | Goat Genomic Resources: The Search for Genes Associated with Its Economic Traits |
| title_sort | goat genomic resources the search for genes associated with its economic traits |
| url | http://dx.doi.org/10.1155/2020/5940205 |
| work_keys_str_mv | AT amamzonaedsiddiki goatgenomicresourcesthesearchforgenesassociatedwithitseconomictraits AT gousmiah goatgenomicresourcesthesearchforgenesassociatedwithitseconomictraits AT mdsirazulislam goatgenomicresourcesthesearchforgenesassociatedwithitseconomictraits AT mahadiakumkum goatgenomicresourcesthesearchforgenesassociatedwithitseconomictraits AT meheadihasanrumi goatgenomicresourcesthesearchforgenesassociatedwithitseconomictraits AT abdulbaten goatgenomicresourcesthesearchforgenesassociatedwithitseconomictraits AT mohammadalamgirhossain goatgenomicresourcesthesearchforgenesassociatedwithitseconomictraits |