Ulcerating Ileocolitis in Severe Amatoxin Poisoning
Amatoxin poisoning is still associated with a great potential for complications and a high mortality. While the occurrence of acute gastroenteritis within the first 24 hours after amatoxin ingestion is well described, only very few descriptions of late gastrointestinal complications of amatoxin pois...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Case Reports in Gastrointestinal Medicine |
| Online Access: | http://dx.doi.org/10.1155/2015/632085 |
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| author | Matthias Peter Hilty Marcel Halama Anne-Katrin Zimmermann Marco Maggiorini Andreas Geier |
| author_facet | Matthias Peter Hilty Marcel Halama Anne-Katrin Zimmermann Marco Maggiorini Andreas Geier |
| author_sort | Matthias Peter Hilty |
| collection | DOAJ |
| description | Amatoxin poisoning is still associated with a great potential for complications and a high mortality. While the occurrence of acute gastroenteritis within the first 24 hours after amatoxin ingestion is well described, only very few descriptions of late gastrointestinal complications of amatoxin poisoning exist worldwide. We present the case of a 57-year-old female patient with severe amatoxin poisoning causing fulminant but reversible hepatic failure that on day 8 after mushroom ingestion developed severe abdominal pain and watery diarrhea. Ulcerating ileocolitis was identified by computed tomography identifying a thickening of the bowel wall of the entire ileum and biopsies taken from the ileum and large bowel revealing distinct ileitis and proximally accentuated colitis. The absence of discernible alternative etiologies such as infectious agents makes a causal relationship between the ulcerating ileocolitis and the amatoxin poisoning likely. Diarrhea and varying abdominal pain persisted over several weeks and clinical follow-up after six months showed a completely symptom-free patient. The case presented highlights the importance to consider the possibility of rare complications of Amanita intoxication in order to be able to respond to them early and adequately. |
| format | Article |
| id | doaj-art-cdaf5f8574fb4dc5afcfcf6db1a079e4 |
| institution | Kabale University |
| issn | 2090-6528 2090-6536 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Gastrointestinal Medicine |
| spelling | doaj-art-cdaf5f8574fb4dc5afcfcf6db1a079e42025-02-03T06:11:25ZengWileyCase Reports in Gastrointestinal Medicine2090-65282090-65362015-01-01201510.1155/2015/632085632085Ulcerating Ileocolitis in Severe Amatoxin PoisoningMatthias Peter Hilty0Marcel Halama1Anne-Katrin Zimmermann2Marco Maggiorini3Andreas Geier4Medical Intensive Care Unit, University Hospital of Zurich, Rämistrasse 100, 8091 Zurich, SwitzerlandDepartment of Gastroenterology and Hepatology, University Hospital of Zurich, Rämistrasse 100, 8091 Zurich, SwitzerlandDepartment of Pathology, University Hospital of Zurich, Rämistrasse 100, 8091 Zurich, SwitzerlandMedical Intensive Care Unit, University Hospital of Zurich, Rämistrasse 100, 8091 Zurich, SwitzerlandDepartment of Gastroenterology and Hepatology, University Hospital of Zurich, Rämistrasse 100, 8091 Zurich, SwitzerlandAmatoxin poisoning is still associated with a great potential for complications and a high mortality. While the occurrence of acute gastroenteritis within the first 24 hours after amatoxin ingestion is well described, only very few descriptions of late gastrointestinal complications of amatoxin poisoning exist worldwide. We present the case of a 57-year-old female patient with severe amatoxin poisoning causing fulminant but reversible hepatic failure that on day 8 after mushroom ingestion developed severe abdominal pain and watery diarrhea. Ulcerating ileocolitis was identified by computed tomography identifying a thickening of the bowel wall of the entire ileum and biopsies taken from the ileum and large bowel revealing distinct ileitis and proximally accentuated colitis. The absence of discernible alternative etiologies such as infectious agents makes a causal relationship between the ulcerating ileocolitis and the amatoxin poisoning likely. Diarrhea and varying abdominal pain persisted over several weeks and clinical follow-up after six months showed a completely symptom-free patient. The case presented highlights the importance to consider the possibility of rare complications of Amanita intoxication in order to be able to respond to them early and adequately.http://dx.doi.org/10.1155/2015/632085 |
| spellingShingle | Matthias Peter Hilty Marcel Halama Anne-Katrin Zimmermann Marco Maggiorini Andreas Geier Ulcerating Ileocolitis in Severe Amatoxin Poisoning Case Reports in Gastrointestinal Medicine |
| title | Ulcerating Ileocolitis in Severe Amatoxin Poisoning |
| title_full | Ulcerating Ileocolitis in Severe Amatoxin Poisoning |
| title_fullStr | Ulcerating Ileocolitis in Severe Amatoxin Poisoning |
| title_full_unstemmed | Ulcerating Ileocolitis in Severe Amatoxin Poisoning |
| title_short | Ulcerating Ileocolitis in Severe Amatoxin Poisoning |
| title_sort | ulcerating ileocolitis in severe amatoxin poisoning |
| url | http://dx.doi.org/10.1155/2015/632085 |
| work_keys_str_mv | AT matthiaspeterhilty ulceratingileocolitisinsevereamatoxinpoisoning AT marcelhalama ulceratingileocolitisinsevereamatoxinpoisoning AT annekatrinzimmermann ulceratingileocolitisinsevereamatoxinpoisoning AT marcomaggiorini ulceratingileocolitisinsevereamatoxinpoisoning AT andreasgeier ulceratingileocolitisinsevereamatoxinpoisoning |