Characteristics of mismatched eplets affecting de novo donor-specific antibody production and antibody-mediated rejection after kidney transplantation

Characteristics of mismatched eplets affecting de novo donor-specific antibody production and antibody-mediated rejection after kidney transplantation

Abstract De novo donor-specific antibody (dnDSA) generation is the most important marker of antibody-mediated rejection (AMR). However, not all dnDSAs induce AMR. The effects of mismatched eplets on dnDSA production and the occurrence AMR remain controversial. We analyzed 64 cases of dnDSA positive...

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Main Authors: Mei-He Li, Gu-Xiang Zhou, Ping Lan, Yi-Xuan Li, Xuan Zhang, Pei-Dan Kuang, Ying Zhang, Ying Wang, Min-Yue Zhang, Xiao-Ming Ding, Wu-Jun Xue, Jin Zheng
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Nephrology
Subjects:
Kidney transplantation
HLA
Eplet
dnDSA
AMR
Online Access:https://doi.org/10.1186/s12882-025-04016-3
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https://doi.org/10.1186/s12882-025-04016-3

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