Left Ventricle Blood Attenuation in Non-Contrast Chest CT Scan as a Clue for Prediction of Anemia
Purpose: One of the indirect methods that has been proposed as a way of the detection of anemia is blood attenuation in non-contrast Computed Tomography (CT) scans. Some indices of non-contrast CT scans have been studied as a clue. Most known of such indices include aortic blood density and the dif...
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Tehran University of Medical Sciences
2025-07-01
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| Series: | Frontiers in Biomedical Technologies |
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| Online Access: | https://fbt.tums.ac.ir/index.php/fbt/article/view/789 |
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| author | Hamid Dahmardeh Aynaz Gerami Mahmoud Khansari Leyla Abdolkarimi Seyede Sara Pakdaman Kolour Majid Ghodsi Hoseinali Danesh Mohamad Ghazanfari Hashemi |
| author_facet | Hamid Dahmardeh Aynaz Gerami Mahmoud Khansari Leyla Abdolkarimi Seyede Sara Pakdaman Kolour Majid Ghodsi Hoseinali Danesh Mohamad Ghazanfari Hashemi |
| author_sort | Hamid Dahmardeh |
| collection | DOAJ |
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Purpose: One of the indirect methods that has been proposed as a way of the detection of anemia is blood attenuation in non-contrast Computed Tomography (CT) scans. Some indices of non-contrast CT scans have been studied as a clue. Most known of such indices include aortic blood density and the difference between blood density and aortic wall density. In the current study, we aimed to evaluate the left ventricle blood attenuation and its relation to patients’ hemoglobin levels.
Materials and Methods: A total of 523 patients who underwent non-contrast chest CT scan with available hemoglobin levels within 48 hours of interval from CT scan acquisition were recruited for this study. Left ventricle blood attenuation was measured and the correlation with hemoglobin levels was evaluated.
Results: There was found to be a linear correlation between blood attenuation in the left ventricle and hemoglobin levels (r=0.33). Our results showed that the highest level of accuracy for diagnosis of anemia is in the Hounsfield Unit of 37.5 for women and 38.5 for men (with 68% sensitivity and 60% specificity) which can be regarded as a reliable threshold.
Conclusion: It can be concluded that the attenuation of the blood in the left ventricle can potentially be a hint for anemia and further evaluation for Hb levels.
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| format | Article |
| id | doaj-art-cd843a2cf7e541e1b2f39c55d5423dd3 |
| institution | Kabale University |
| issn | 2345-5837 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Frontiers in Biomedical Technologies |
| spelling | doaj-art-cd843a2cf7e541e1b2f39c55d5423dd32025-08-20T03:41:10ZengTehran University of Medical SciencesFrontiers in Biomedical Technologies2345-58372025-07-0112310.18502/fbt.v12i3.19170Left Ventricle Blood Attenuation in Non-Contrast Chest CT Scan as a Clue for Prediction of AnemiaHamid Dahmardeh0Aynaz Gerami1Mahmoud Khansari2Leyla Abdolkarimi3Seyede Sara Pakdaman Kolour4Majid Ghodsi5Hoseinali Danesh6Mohamad Ghazanfari Hashemi7Department of Radiology, School of Medicine, Zahedan University of Medical Sciences, Zahedan, IranSchool of Medicine, Tehran University of Medical Sciences, Tehran, IranDepartment of General Surgery, School of Medicine, Tehran University of Medical Sciences, Tehran, IranRajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, IranDepartment of Internal Medicine, Faculty of Medicine, Guilan University of Medical Sciences, Rasht, IranDepartment of Surgery, School of Medicine, Sabzevar University of Medical Sciences, Sabzevar, IranPlastic, Reconstructive & Aesthetic Surgeon, Associate professor of Zahedan University of Medical Sciences, Clinical Immunology Research Center at Zahedan University of Medical Science, Zahedan, IranDepartment of Radiology, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran Purpose: One of the indirect methods that has been proposed as a way of the detection of anemia is blood attenuation in non-contrast Computed Tomography (CT) scans. Some indices of non-contrast CT scans have been studied as a clue. Most known of such indices include aortic blood density and the difference between blood density and aortic wall density. In the current study, we aimed to evaluate the left ventricle blood attenuation and its relation to patients’ hemoglobin levels. Materials and Methods: A total of 523 patients who underwent non-contrast chest CT scan with available hemoglobin levels within 48 hours of interval from CT scan acquisition were recruited for this study. Left ventricle blood attenuation was measured and the correlation with hemoglobin levels was evaluated. Results: There was found to be a linear correlation between blood attenuation in the left ventricle and hemoglobin levels (r=0.33). Our results showed that the highest level of accuracy for diagnosis of anemia is in the Hounsfield Unit of 37.5 for women and 38.5 for men (with 68% sensitivity and 60% specificity) which can be regarded as a reliable threshold. Conclusion: It can be concluded that the attenuation of the blood in the left ventricle can potentially be a hint for anemia and further evaluation for Hb levels. https://fbt.tums.ac.ir/index.php/fbt/article/view/789Non-Contrast Computed Tomography ScanAnemiaAnemia PredictionHounsfield UnitLeft Ventricle Attenuation |
| spellingShingle | Hamid Dahmardeh Aynaz Gerami Mahmoud Khansari Leyla Abdolkarimi Seyede Sara Pakdaman Kolour Majid Ghodsi Hoseinali Danesh Mohamad Ghazanfari Hashemi Left Ventricle Blood Attenuation in Non-Contrast Chest CT Scan as a Clue for Prediction of Anemia Frontiers in Biomedical Technologies Non-Contrast Computed Tomography Scan Anemia Anemia Prediction Hounsfield Unit Left Ventricle Attenuation |
| title | Left Ventricle Blood Attenuation in Non-Contrast Chest CT Scan as a Clue for Prediction of Anemia |
| title_full | Left Ventricle Blood Attenuation in Non-Contrast Chest CT Scan as a Clue for Prediction of Anemia |
| title_fullStr | Left Ventricle Blood Attenuation in Non-Contrast Chest CT Scan as a Clue for Prediction of Anemia |
| title_full_unstemmed | Left Ventricle Blood Attenuation in Non-Contrast Chest CT Scan as a Clue for Prediction of Anemia |
| title_short | Left Ventricle Blood Attenuation in Non-Contrast Chest CT Scan as a Clue for Prediction of Anemia |
| title_sort | left ventricle blood attenuation in non contrast chest ct scan as a clue for prediction of anemia |
| topic | Non-Contrast Computed Tomography Scan Anemia Anemia Prediction Hounsfield Unit Left Ventricle Attenuation |
| url | https://fbt.tums.ac.ir/index.php/fbt/article/view/789 |
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