Synthesis and Antimicrobial Activity ofSome New 2-Substituted Benzothiazole Derivatives

Some new 2-(5-substituted-1,3,4-oxadiazole-2-yl)-1,3- benzothiazole (3a-j) were synthesized by refluxing benzothiazolyl carboxyhydrazide with different aryl acids in phosphoryl chloride. Structures of the synthesized compounds were established on the basis of 1H NMR and Mass spectral data. The anti...

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Main Authors: B. Rajeeva, N. Srinivasulu, S. M. Shantakumar
Format: Article
Language:English
Published: Wiley 2009-01-01
Series:E-Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2009/404596
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author B. Rajeeva
N. Srinivasulu
S. M. Shantakumar
author_facet B. Rajeeva
N. Srinivasulu
S. M. Shantakumar
author_sort B. Rajeeva
collection DOAJ
description Some new 2-(5-substituted-1,3,4-oxadiazole-2-yl)-1,3- benzothiazole (3a-j) were synthesized by refluxing benzothiazolyl carboxyhydrazide with different aryl acids in phosphoryl chloride. Structures of the synthesized compounds were established on the basis of 1H NMR and Mass spectral data. The anti microbial activity of the synthesized compounds was evaluated by disc diffusion method.
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institution Kabale University
issn 0973-4945
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publishDate 2009-01-01
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record_format Article
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spelling doaj-art-cd6c67721c4a46f1937cf737fb9271932025-02-03T06:08:27ZengWileyE-Journal of Chemistry0973-49452090-98102009-01-016377577910.1155/2009/404596Synthesis and Antimicrobial Activity ofSome New 2-Substituted Benzothiazole DerivativesB. Rajeeva0N. Srinivasulu1S. M. Shantakumar2Department of Pharmaceutical Chemistry, V. L. College of Pharmacy, Raichur-584103, Karnataka, IndiaDepartment of Pharmaceutical Chemistry, V. L. College of Pharmacy, Raichur-584103, Karnataka, IndiaDepartment of Pharmaceutical Chemistry, V. L. College of Pharmacy, Raichur-584103, Karnataka, IndiaSome new 2-(5-substituted-1,3,4-oxadiazole-2-yl)-1,3- benzothiazole (3a-j) were synthesized by refluxing benzothiazolyl carboxyhydrazide with different aryl acids in phosphoryl chloride. Structures of the synthesized compounds were established on the basis of 1H NMR and Mass spectral data. The anti microbial activity of the synthesized compounds was evaluated by disc diffusion method.http://dx.doi.org/10.1155/2009/404596
spellingShingle B. Rajeeva
N. Srinivasulu
S. M. Shantakumar
Synthesis and Antimicrobial Activity ofSome New 2-Substituted Benzothiazole Derivatives
E-Journal of Chemistry
title Synthesis and Antimicrobial Activity ofSome New 2-Substituted Benzothiazole Derivatives
title_full Synthesis and Antimicrobial Activity ofSome New 2-Substituted Benzothiazole Derivatives
title_fullStr Synthesis and Antimicrobial Activity ofSome New 2-Substituted Benzothiazole Derivatives
title_full_unstemmed Synthesis and Antimicrobial Activity ofSome New 2-Substituted Benzothiazole Derivatives
title_short Synthesis and Antimicrobial Activity ofSome New 2-Substituted Benzothiazole Derivatives
title_sort synthesis and antimicrobial activity ofsome new 2 substituted benzothiazole derivatives
url http://dx.doi.org/10.1155/2009/404596
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AT nsrinivasulu synthesisandantimicrobialactivityofsomenew2substitutedbenzothiazolederivatives
AT smshantakumar synthesisandantimicrobialactivityofsomenew2substitutedbenzothiazolederivatives