Separable Roles for a Caenorhabditis elegans RMI1 Homolog in Promoting and Antagonizing Meiotic Crossovers Ensure Faithful Chromosome Inheritance.

Separable Roles for a Caenorhabditis elegans RMI1 Homolog in Promoting and Antagonizing Meiotic Crossovers Ensure Faithful Chromosome Inheritance.

During the first meiotic division, crossovers (COs) between homologous chromosomes ensure their correct segregation. COs are produced by homologous recombination (HR)-mediated repair of programmed DNA double strand breaks (DSBs). As more DSBs are induced than COs, mechanisms are required to establis...

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Main Authors: Marlène Jagut, Patricia Hamminger, Alexander Woglar, Sophia Millonigg, Luis Paulin, Martin Mikl, Maria Rosaria Dello Stritto, Lois Tang, Cornelia Habacher, Angela Tam, Miguel Gallach, Arndt von Haeseler, Anne M Villeneuve, Verena Jantsch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-03-01
Series:PLoS Biology
Online Access:https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.1002412&type=printable
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