Role of Paraoxonase 2 in Airway Epithelial Response to Oxidant Stress

Role of Paraoxonase 2 in Airway Epithelial Response to Oxidant Stress

Asthma is a widespread chronic lung disease characterized by airway inflammation and hyperresponsiveness. This airway inflammation is classified by either the presence (T2-high) or absence (T2-low) of high levels of eosinophils. Because most therapies for asthma target eosinophils and related pathwa...

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Main Authors: Matthew S. McCravy, Zhonghui Yang, Jaime Cyphert-Daly, Zachary R. Healy, Aaron V. Vose, Haein R. Kim, Julia K. L. Walker, Robert M. Tighe, Heath G. Gasier, Jennifer L. Ingram, Loretta G. Que
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Antioxidants
Subjects:
asthma
ozone
paraoxonase
oxidant stress
mitochondria
Online Access:https://www.mdpi.com/2076-3921/13/11/1333
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