Case report: Testicular manifestation of ANCA vasculitis
ANCA-associated vasculitis is a rare autoimmune disorder affecting small to medium-sized vessels, often targeting the respiratory tract and kidneys. Testicular involvement is rare and can resemble malignancy, leading to unnecessary surgery. A 36-year-old male presented with painful fingers, oral and...
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| Language: | English |
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Elsevier
2025-03-01
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| Series: | Urology Case Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214442025000373 |
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| author | Noah J. Sandel Henry Wielzen |
| author_facet | Noah J. Sandel Henry Wielzen |
| author_sort | Noah J. Sandel |
| collection | DOAJ |
| description | ANCA-associated vasculitis is a rare autoimmune disorder affecting small to medium-sized vessels, often targeting the respiratory tract and kidneys. Testicular involvement is rare and can resemble malignancy, leading to unnecessary surgery. A 36-year-old male presented with painful fingers, oral and nasal ulcers, and knee arthritis. Elevated proteinase 3 (PR3) antibodies confirmed PR3 ANCA-associated vasculitis. During hospitalization, patient developed testicular pain, and an ultrasound raised suspicion of malignancy. An inguinal orchidectomy was performed, revealing inflammation consistent with vasculitis, but no malignancy. Testicular involvement in ANCA vasculitis can mimic cancer, and increased awareness may help prevent unnecessary surgical procedures. |
| format | Article |
| id | doaj-art-cd0cac9c18564801ab2a341405c19fc7 |
| institution | Kabale University |
| issn | 2214-4420 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Urology Case Reports |
| spelling | doaj-art-cd0cac9c18564801ab2a341405c19fc72025-02-03T04:16:43ZengElsevierUrology Case Reports2214-44202025-03-0159102966Case report: Testicular manifestation of ANCA vasculitisNoah J. Sandel0Henry Wielzen1Corresponding author. Department of Urology, Amsterdam UMC, University of Amsterdam, De Boelelaan 1117, Amsterdam, Noord-Holland, 1081HV, the Netherlands.; Department of Urology, Amsterdam UMC, University of Amsterdam, Amsterdam, the NetherlandsDepartment of Urology, Amsterdam UMC, University of Amsterdam, Amsterdam, the NetherlandsANCA-associated vasculitis is a rare autoimmune disorder affecting small to medium-sized vessels, often targeting the respiratory tract and kidneys. Testicular involvement is rare and can resemble malignancy, leading to unnecessary surgery. A 36-year-old male presented with painful fingers, oral and nasal ulcers, and knee arthritis. Elevated proteinase 3 (PR3) antibodies confirmed PR3 ANCA-associated vasculitis. During hospitalization, patient developed testicular pain, and an ultrasound raised suspicion of malignancy. An inguinal orchidectomy was performed, revealing inflammation consistent with vasculitis, but no malignancy. Testicular involvement in ANCA vasculitis can mimic cancer, and increased awareness may help prevent unnecessary surgical procedures.http://www.sciencedirect.com/science/article/pii/S2214442025000373ANCA vasculitisTesticular malignancyTesticular cancerVasculitisOrchidectomy |
| spellingShingle | Noah J. Sandel Henry Wielzen Case report: Testicular manifestation of ANCA vasculitis Urology Case Reports ANCA vasculitis Testicular malignancy Testicular cancer Vasculitis Orchidectomy |
| title | Case report: Testicular manifestation of ANCA vasculitis |
| title_full | Case report: Testicular manifestation of ANCA vasculitis |
| title_fullStr | Case report: Testicular manifestation of ANCA vasculitis |
| title_full_unstemmed | Case report: Testicular manifestation of ANCA vasculitis |
| title_short | Case report: Testicular manifestation of ANCA vasculitis |
| title_sort | case report testicular manifestation of anca vasculitis |
| topic | ANCA vasculitis Testicular malignancy Testicular cancer Vasculitis Orchidectomy |
| url | http://www.sciencedirect.com/science/article/pii/S2214442025000373 |
| work_keys_str_mv | AT noahjsandel casereporttesticularmanifestationofancavasculitis AT henrywielzen casereporttesticularmanifestationofancavasculitis |