L-NAME causes antinociception by stimulation of the arginine-NO-cGMP pathway
NG-nitro-L-arginine methyl ester (L-NAME) has been used extensively as a paradigmatic inhibitor of NO synthase and has been shown to cause antinociception in several experimental models. We describe here how L-NAME produced a dose-dependent anti-nociceptive effect when injected intraperitoneally in...
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| Main Authors: | I. D. G. Duarte, S. H. Ferreira |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2000-01-01
|
| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1080/09629350050024348 |
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