LSM2 drives glioma progression through alternative splicing dysregulation: a multi-omics approach to identify a potential therapeutic target
BackgroundGlioma, particularly glioblastoma (GBM), remains a highly aggressive and challenging tumour, characterised by poor prognosis and limited therapeutic options. LSM2, an RNA-binding protein, has been implicated in tumour progression, yet its role in glioma remains underexplored. This study ai...
Saved in:
| Main Authors: | Cao Yang, Chang Ge, Wenjie Zhang, Jingxuan Xu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-04-01
|
| Series: | Frontiers in Oncology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2025.1521608/full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Multi-omics landscape of alternative splicing in diffuse midline glioma reveals immune- and neural-driven subtypes with implications for spliceosome-targeted therapy
by: Chaxian Liu, et al.
Published: (2025-04-01) -
Prognostic implications of alternative splicing events and key splicing factors in head and neck squamous cell carcinoma
by: Siyi He, et al.
Published: (2025-03-01) -
Epigenetic Regulation and Therapeutic Targeting of Alternative Splicing Dysregulation in Cancer
by: Yan Lei, et al.
Published: (2025-05-01) -
Dysregulation and Therapeutic Targeting of RNA Splicing Variants in Cancer
by: Doaa Rabaya, et al.
Published: (2024-09-01) -
Alternative splicing in ovarian cancer
by: Liwei Wei, et al.
Published: (2024-10-01)