Detecting genetic interactions with visible neural networks

Abstract Non-linear interactions among single nucleotide polymorphisms (SNPs), genes, and pathways play an important role in human diseases, but identifying these interactions is a challenging task. Neural networks are state-of-the-art predictors in many domains due to their ability to analyze big d...

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Bibliographic Details
Main Authors: Arno van Hilten, Federico Melograna, Bowen Fan, Wiro Niessen, Kristel van Steen, Gennady Roshchupkin
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08157-x
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