Anti-Inflammatory Properties of Dendrimers per se
Dendrimers are polybranched and polyfunctionalized tree-like polymers. Unlike linear polymers, they have perfectly defined structure and molecular weight, due to their iterative step-by-step synthesis. Their multivalent structure and supramolecular properties have made them attractive nanotools for...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1100/tsw.2011.129 |
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| _version_ | 1832549542520684544 |
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| author | Myriam Hayder Séverine Fruchon Jean-Jacques Fournié Mary Poupot Rémy Poupot |
| author_facet | Myriam Hayder Séverine Fruchon Jean-Jacques Fournié Mary Poupot Rémy Poupot |
| author_sort | Myriam Hayder |
| collection | DOAJ |
| description | Dendrimers are polybranched and polyfunctionalized tree-like polymers. Unlike linear polymers, they have perfectly defined structure and molecular weight, due to their iterative step-by-step synthesis. Their multivalent structure and supramolecular properties have made them attractive nanotools for applications, particularly in biology and medicine. Among the different biological and medical properties of dendrimers that have been developed over the past decades, the anti-inflammatory properties of several groups of dendrimers are the most recently discovered. Thereof, dendrimers emerge as promising, although heretical, drug candidates for the treatment of still-uncured chronic inflammatory disorders. This mini-review is based on the five main scientific articles giving an overview of what can be the spectrum of anti-inflammatory characteristics displayed by dendrimers. |
| format | Article |
| id | doaj-art-ccb5a739d422465da77265174a8b4be2 |
| institution | Kabale University |
| issn | 1537-744X |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-ccb5a739d422465da77265174a8b4be22025-02-03T06:11:08ZengWileyThe Scientific World Journal1537-744X2011-01-01111367138210.1100/tsw.2011.129Anti-Inflammatory Properties of Dendrimers per seMyriam Hayder0Séverine Fruchon1Jean-Jacques Fournié2Mary Poupot3Rémy Poupot4Inserm, U1043, CNRS, U5282 and Université de Toulouse, UPS, Centre de Physiopathologie de Toulouse Purpan (CPTP), Toulouse, F-31300, FranceInserm, U1043, CNRS, U5282 and Université de Toulouse, UPS, Centre de Physiopathologie de Toulouse Purpan (CPTP), Toulouse, F-31300, FranceInserm, U1037, CNRS, U5282 and Université de Toulouse, UPS, Centre de Recherche en Cancérologie de Toulouse (CRCT), Toulouse, F-31300, FranceInserm, U1037, CNRS, U5282 and Université de Toulouse, UPS, Centre de Recherche en Cancérologie de Toulouse (CRCT), Toulouse, F-31300, FranceInserm, U1043, CNRS, U5282 and Université de Toulouse, UPS, Centre de Physiopathologie de Toulouse Purpan (CPTP), Toulouse, F-31300, FranceDendrimers are polybranched and polyfunctionalized tree-like polymers. Unlike linear polymers, they have perfectly defined structure and molecular weight, due to their iterative step-by-step synthesis. Their multivalent structure and supramolecular properties have made them attractive nanotools for applications, particularly in biology and medicine. Among the different biological and medical properties of dendrimers that have been developed over the past decades, the anti-inflammatory properties of several groups of dendrimers are the most recently discovered. Thereof, dendrimers emerge as promising, although heretical, drug candidates for the treatment of still-uncured chronic inflammatory disorders. This mini-review is based on the five main scientific articles giving an overview of what can be the spectrum of anti-inflammatory characteristics displayed by dendrimers.http://dx.doi.org/10.1100/tsw.2011.129 |
| spellingShingle | Myriam Hayder Séverine Fruchon Jean-Jacques Fournié Mary Poupot Rémy Poupot Anti-Inflammatory Properties of Dendrimers per se The Scientific World Journal |
| title | Anti-Inflammatory Properties of Dendrimers per se |
| title_full | Anti-Inflammatory Properties of Dendrimers per se |
| title_fullStr | Anti-Inflammatory Properties of Dendrimers per se |
| title_full_unstemmed | Anti-Inflammatory Properties of Dendrimers per se |
| title_short | Anti-Inflammatory Properties of Dendrimers per se |
| title_sort | anti inflammatory properties of dendrimers per se |
| url | http://dx.doi.org/10.1100/tsw.2011.129 |
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