Ticlopidine in Its Prodrug Form Is a Selective Inhibitor of Human NTPDase1
Nucleoside triphosphate diphosphohydrolase-1 (NTPDase1), like other ectonucleotidases, controls extracellular nucleotide levels and consequently their (patho)physiological responses such as in thrombosis, inflammation, and cancer. Selective NTPDase1 inhibitors would therefore be very useful. We prev...
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Main Authors: | Joanna Lecka, Michel Fausther, Beat Künzli, Jean Sévigny |
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Format: | Article |
Language: | English |
Published: |
Wiley
2014-01-01
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Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1155/2014/547480 |
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