Anti-GBM of Pregnancy: Acute Renal Failure Resolved after Spontaneous Abortion, Plasma Exchange, Hemodialysis, and Steroids

Antiglomerular basement membrane disease presenting during pregnancy is very uncommon. We present a case of a pregnant female who presented with acute renal failure needing dialysis from Goodpasture’s disease. She responded very well to just plasma exchange, high dose steroids, and hemodialysis. Cyc...

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Main Authors: Mohammed Muqeet Adnan, Jordan Morton, Syed Hashmi, Sufyan Abdul Mujeeb, William Kern, Benjamin Jr. Cowley
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Case Reports in Nephrology
Online Access:http://dx.doi.org/10.1155/2014/243746
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author Mohammed Muqeet Adnan
Jordan Morton
Syed Hashmi
Sufyan Abdul Mujeeb
William Kern
Benjamin Jr. Cowley
author_facet Mohammed Muqeet Adnan
Jordan Morton
Syed Hashmi
Sufyan Abdul Mujeeb
William Kern
Benjamin Jr. Cowley
author_sort Mohammed Muqeet Adnan
collection DOAJ
description Antiglomerular basement membrane disease presenting during pregnancy is very uncommon. We present a case of a pregnant female who presented with acute renal failure needing dialysis from Goodpasture’s disease. She responded very well to just plasma exchange, high dose steroids, and hemodialysis. Cyclophosphamide was never started on this patient. She had a spontaneous abortion in her 8th week of pregnancy and henceforth did very well to regain her renal function. Patient became hemodialysis independent at 2 months and returned to her baseline kidney function at 6 months. We present this remarkable case of recovery from acute renal failure in a patient with anti-GBM disease. We think the flare-up of renal failure was pregnancy related which resolved after spontaneous abortion.
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publishDate 2014-01-01
publisher Wiley
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series Case Reports in Nephrology
spelling doaj-art-cc86ac1d6c61476584a33d15a63234ed2025-02-03T01:31:32ZengWileyCase Reports in Nephrology2090-66412090-665X2014-01-01201410.1155/2014/243746243746Anti-GBM of Pregnancy: Acute Renal Failure Resolved after Spontaneous Abortion, Plasma Exchange, Hemodialysis, and SteroidsMohammed Muqeet Adnan0Jordan Morton1Syed Hashmi2Sufyan Abdul Mujeeb3William Kern4Benjamin Jr. Cowley5Department of Internal Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73117, USADepartment of Internal Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73117, USADepartment of Internal Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73117, USAUniversity of Illinois at Chicago, Chicago, IL 60612, USADepartment of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73117, USADepartment of Nephrology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73117, USAAntiglomerular basement membrane disease presenting during pregnancy is very uncommon. We present a case of a pregnant female who presented with acute renal failure needing dialysis from Goodpasture’s disease. She responded very well to just plasma exchange, high dose steroids, and hemodialysis. Cyclophosphamide was never started on this patient. She had a spontaneous abortion in her 8th week of pregnancy and henceforth did very well to regain her renal function. Patient became hemodialysis independent at 2 months and returned to her baseline kidney function at 6 months. We present this remarkable case of recovery from acute renal failure in a patient with anti-GBM disease. We think the flare-up of renal failure was pregnancy related which resolved after spontaneous abortion.http://dx.doi.org/10.1155/2014/243746
spellingShingle Mohammed Muqeet Adnan
Jordan Morton
Syed Hashmi
Sufyan Abdul Mujeeb
William Kern
Benjamin Jr. Cowley
Anti-GBM of Pregnancy: Acute Renal Failure Resolved after Spontaneous Abortion, Plasma Exchange, Hemodialysis, and Steroids
Case Reports in Nephrology
title Anti-GBM of Pregnancy: Acute Renal Failure Resolved after Spontaneous Abortion, Plasma Exchange, Hemodialysis, and Steroids
title_full Anti-GBM of Pregnancy: Acute Renal Failure Resolved after Spontaneous Abortion, Plasma Exchange, Hemodialysis, and Steroids
title_fullStr Anti-GBM of Pregnancy: Acute Renal Failure Resolved after Spontaneous Abortion, Plasma Exchange, Hemodialysis, and Steroids
title_full_unstemmed Anti-GBM of Pregnancy: Acute Renal Failure Resolved after Spontaneous Abortion, Plasma Exchange, Hemodialysis, and Steroids
title_short Anti-GBM of Pregnancy: Acute Renal Failure Resolved after Spontaneous Abortion, Plasma Exchange, Hemodialysis, and Steroids
title_sort anti gbm of pregnancy acute renal failure resolved after spontaneous abortion plasma exchange hemodialysis and steroids
url http://dx.doi.org/10.1155/2014/243746
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