Selective Phenome Growth Adapted NK Model: A Novel Landscape to Represent Aptamer Ligand Binding

Selective Phenome Growth Adapted NK Model: A Novel Landscape to Represent Aptamer Ligand Binding

Aptamers are single-stranded oligonucleotides selected by evolutionary approaches from massive libraries with significant potential for specific molecular recognition in diagnostics and therapeutics. A complete empirical characterisation of an aptamer selection experiment is not feasible due to the...

Full description

Saved in:

Bibliographic Details
Main Authors:	Andrew Brian Kinghorn, Julian Alexander Tanner
Format:	Article
Language:	English
Published:	Wiley 2017-01-01
Series:	Complexity
Online Access:	http://dx.doi.org/10.1155/2017/6760852
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Phenomic characterization of Crotalaria germplasm for crop improvement
by: Joshua Kiilu Muli, et al.
Published: (2021-03-01)

Evaluation of genomic and phenomic prediction for application in apple breeding
by: Michaela Jung, et al.
Published: (2025-01-01)

Nucleic-Acid-Binding Chromophores as Efficient Indicators of Aptamer-Target Interactions
by: Kwabena Sarpong, et al.
Published: (2012-01-01)

Phenome-wide association studies between SERINC2 and neuropsychiatric disorders
by: Ping Liu, et al.
Published: (2025-01-01)

Capture-SELEX: Selection of DNA Aptamers for Aminoglycoside Antibiotics
by: Regina Stoltenburg, et al.
Published: (2012-01-01)

Selective and Sensitive Fluorescence Aptamer Biosensors of Adenosine Triphosphate
by: Chao Meng, et al.
Published: (2016-05-01)

Direct Detection of Thrombin Binding to 8-Bromodeoxyguanosine-Modified Aptamer: Effects of Modification on Affinity and Kinetics
by: Shou Goji, et al.
Published: (2011-01-01)

The Evidence of Cooperative Binding of a Ligand to G4 DNA
by: A. G. Kudrev
Published: (2017-01-01)

The Memories of NK Cells: Innate-Adaptive Immune Intrinsic Crosstalk
by: Sara Gabrielli, et al.
Published: (2016-01-01)

Sensitivity and Selectivity on Aptamer-Based Assay: The Determination of Tetracycline Residue in Bovine Milk
by: Sohee Jeong, et al.
Published: (2012-01-01)

Effect of Common Buffers and Heterocyclic Ligands on the Binding of Cu(II) at the Multimetal Binding Site in Human Serum Albumin
by: Magdalena Sokołowska, et al.
Published: (2010-01-01)

DeepAptamer: Advancing high-affinity aptamer discovery with a hybrid deep learning model
by: Xin Yang, et al.
Published: (2025-03-01)

Selection of DNA Aptamers for Ovarian Cancer Biomarker CA125 Using One-Pot SELEX and High-Throughput Sequencing
by: Delia J. Scoville, et al.
Published: (2017-01-01)

Development of a Novel Fluorescence Assay Based on the Use of the Thrombin-Binding Aptamer for the Detection of O6-Alkylguanine-DNA Alkyltransferase Activity
by: Maria Tintoré, et al.
Published: (2010-01-01)

Cell-Specific Aptamers as Emerging Therapeutics
by: Cindy Meyer, et al.
Published: (2011-01-01)

RETRACTED ARTICLE: Medical history predicts phenome-wide disease onset and enables the rapid response to emerging health threats
by: Jakob Steinfeldt, et al.
Published: (2024-05-01)

Machine learning approaches for predicting protein-ligand binding sites from sequence data
by: Orhun Vural, et al.
Published: (2025-02-01)

Effective in vivo binding energy landscape illustrates kinetic stability of RBPJ-DNA binding
by: Duyen Huynh, et al.
Published: (2025-02-01)

Aptamers: A Feasible Technology in Cancer Immunotherapy
by: M. M. Soldevilla, et al.
Published: (2016-01-01)

Structure-based insights into fluorogenic RNA aptamers
by: Song Qianqian, et al.
Published: (2024-08-01)

Development of Murine Hepatic NK Cells during Ontogeny: Comparison with Spleen NK Cells
by: Xian Wu, et al.
Published: (2012-01-01)

Allosteric coupling between G‐protein binding and extracellular ligand binding sites in GPR52 revealed by 19F‐NMR and cryo‐electron microscopy
by: Yanliu Fan, et al.
Published: (2023-04-01)

G Protein-Coupled Estrogen Receptor-Selective Ligands Modulate Endometrial Tumor Growth
by: Whitney K. Petrie, et al.
Published: (2013-01-01)

Using Protein Painting Mass Spectrometry to Define Ligand Receptor Interaction Sites for Acetylcholine Binding Protein
by: Alexandru Graur, et al.
Published: (2025-01-01)

Synthesis, Characterization, DNA Binding, and Photocleavage Activity of Oxorhenium (V) Complexes with α-Diimine and Quinoxaline Ligands
by: Christiana A. Mitsopoulou, et al.
Published: (2010-01-01)

The algebraic extended atom-type graph-based model for precise ligand–receptor binding affinity prediction
by: Farjana Tasnim Mukta, et al.
Published: (2025-01-01)

Peptide Aptamer–Paclitaxel Conjugates for Tumor Targeted Therapy
by: Xinyang Shen, et al.
Published: (2024-12-01)

Nucleic Acid Aptamers for Human Norovirus GII.4 and GII.17 Virus-Like Particles (VLPs) Exhibit Specific Binding and Inhibit VLPs from Entering Cells
by: Cheng C, et al.
Published: (2025-02-01)

Synthesis, Characterization, Biological Activity and DNA Binding Studies of Metal Complexes with 4-Aminoantipyrine Schiff Base Ligand
by: B. Anupama, et al.
Published: (2012-01-01)

Targeting RGMb interactions: Discovery and preclinical characterization of potent anti-RGMb antibodies blocking multiple ligand bindings
by: Maria Meira, et al.
Published: (2024-12-01)

Microarrays as Model Biosensor Platforms to Investigate the Structure and Affinity of Aptamers
by: Jennifer A. Martin, et al.
Published: (2016-01-01)

Molecular Programming Design of Glyconucleic Acid Aptamer with High Stability
by: Yongqi Han, et al.
Published: (2025-01-01)

Machine learning-powered, high-affinity modification strategies for aptamers
by: Gubu Amu, et al.
Published: (2025-01-01)

Synthesis, Crystal Structure, and DNA-Binding Studies of a Nickel(II) Complex with the Bis(2-benzimidazolymethyl)amine Ligand
by: Huilu Wu, et al.
Published: (2012-01-01)

The landscape of alternative polyadenylation during EMT and its regulation by the RNA-binding protein Quaking
by: Daniel P. Neumann, et al.
Published: (2024-12-01)

Fragmenstein: predicting protein–ligand structures of compounds derived from known crystallographic fragment hits using a strict conserved-binding–based methodology
by: Matteo P. Ferla, et al.
Published: (2025-01-01)

The Role of NK Cells in Pig-to-Human Xenotransplantation
by: Gisella Puga Yung, et al.
Published: (2017-01-01)

NK-DC Crosstalk in Immunity to Microbial Infection
by: Rony Thomas, et al.
Published: (2016-01-01)

Single-Round Patterned DNA Library Microarray Aptamer Lead Identification
by: Jennifer A. Martin, et al.
Published: (2015-01-01)

Method to Determine the Optimal Aptamer-to-Bead Ratio by Using Flow Cytometry
by: Sun Young Lee, et al.
Published: (2023-01-01)