Oxidized Low-Density Lipoprotein as a Potential Target for Enhancing Immune Checkpoint Inhibitor Therapy in Microsatellite-Stable Colorectal Cancer

Oxidized Low-Density Lipoprotein as a Potential Target for Enhancing Immune Checkpoint Inhibitor Therapy in Microsatellite-Stable Colorectal Cancer

Oxidized low-density lipoprotein (oxLDL) exhibits differential expression in microsatellite-stable (MSS) and microsatellite instability-high (MSI) colorectal cancer (CRC), highlighting its potential therapeutic role in immune checkpoint inhibitor (ICI) resistance in MSS CRC. Elevated oxLDL levels in...

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Bibliographic Details
Main Authors:	Xiaochun Zhang, Xiaorui Ye, Heiying Jin
Format:	Article
Language:	English
Published:	MDPI AG 2025-06-01
Series:	Antioxidants
Subjects:	oxidized low-density lipoprotein microsatellite-stable colorectal cancer immune checkpoint inhibitors tumor microenvironment metabolic reprogramming immunosuppression
Online Access:	https://www.mdpi.com/2076-3921/14/6/726
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