The Relationship Between the Modified Glasgow Prognostic and SYNTAX Scores in Patients with Non-ST Elevation Myocardial Infarction
Objective: This study investigated the modified Glasgow prognostic score (mGPS) to determine its predictive value and how it could be compared with various inflammatory markers, including C-reactive protein (CRP) to albumin ratio and neutrophil-to-lymphocyte ratio, for determining the extent and sev...
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| Format: | Article |
| Language: | English |
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Galenos Publishing House
2024-09-01
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| Series: | Medeniyet Medical Journal |
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| Online Access: | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=medeniyet&un=MEDJ-32585 |
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| author | Ahmet KARADUMAN Cemalettin YILMAZ Mustafa Ferhat KETEN Ismail BALABAN Zeynep Esra GUNER Mehmet CELIK |
| author_facet | Ahmet KARADUMAN Cemalettin YILMAZ Mustafa Ferhat KETEN Ismail BALABAN Zeynep Esra GUNER Mehmet CELIK |
| author_sort | Ahmet KARADUMAN |
| collection | DOAJ |
| description | Objective: This study investigated the modified Glasgow prognostic score (mGPS) to determine its predictive value and how it could be compared with various inflammatory markers, including C-reactive protein (CRP) to albumin ratio and neutrophil-to-lymphocyte ratio, for determining the extent and severity of coronary artery disease (CAD) in patients with non-ST-elevated myocardial infarction (NSTEMI).
Methods: This study analyzed the cases of 295 patients with NSTEMI who had undergone coronary angiography. In an effort to determine the seriousness and scope of CAD in each patient, the Synergy between Percutaneous Coronary Intervention with Taxus and Cardiac Surgery (SYNTAX) score was calculated and then assessed. The study sample was divided into two separate groups based on the SYNTAX score: moderate to high SYNTAX (>22) and low SYNTAX (≤22).
Results: There were 295 patients (23.1% female, 76.9% male) included in the research, with an average age being 61.2+-10.9 years, and the mean SYNTAX score being 7.3+-10.4 (range: 0-40). Those with a SYNTAX score >22 were observed to possess significantly higher levels of CRP, CRP/albumin ratio, and mean mGPS 1-2 ratios compared with those with a SYNTAX score ≤22 (all p<0.001). Smoking [odds ratio (OR): 3.341, 95% confidence interval (CI): 1.531-7.294; p=0.002], CRP/albumin ratio (OR: 4.958, 95% CI: 1.335-18.418; p=0.017), and mGPS score of 1-2 (OR: 3.121, 95% CI: 1.430-6.814; p=0.004) were independent factors used to help predict a high SYNTAX score.
Conclusions: It seems possible to make use of the mGPS when estimating the degree and intricacies of CAD in patients with NSTEMI, as there appears to be a connection with higher SYNTAX scores. |
| format | Article |
| id | doaj-art-cc687a210981497ba6ddb4adb8511b49 |
| institution | Kabale University |
| issn | 2149-2042 2149-4606 |
| language | English |
| publishDate | 2024-09-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | Medeniyet Medical Journal |
| spelling | doaj-art-cc687a210981497ba6ddb4adb8511b492025-01-29T10:22:46ZengGalenos Publishing HouseMedeniyet Medical Journal2149-20422149-46062024-09-0139317518210.4274/MMJ.galenos.2024.32585MEDJ-32585The Relationship Between the Modified Glasgow Prognostic and SYNTAX Scores in Patients with Non-ST Elevation Myocardial InfarctionAhmet KARADUMAN0Cemalettin YILMAZ1Mustafa Ferhat KETEN2Ismail BALABAN3Zeynep Esra GUNER4Mehmet CELIK5Tatvan State Hospital, Clinic of Cardiology, Bitlis, TürkiyeMalazgirt State Hospital, Clinic of Cardiology, Mus, TürkiyeUniversity of Health Sciences Türkiye, Kartal Kosuyolu Yuksek Ihtisas Training and Research Hospital, Clinic of Cardiology, Istanbul, TürkiyeUniversity of Health Sciences Türkiye, Kartal Kosuyolu Yuksek Ihtisas Training and Research Hospital, Clinic of Cardiology, Istanbul, TürkiyeUniversity of Health Sciences Türkiye, Kartal Kosuyolu Yuksek Ihtisas Training and Research Hospital, Clinic of Cardiology, Istanbul, TürkiyeUniversity of Health Sciences Türkiye, Kartal Kosuyolu Yuksek Ihtisas Training and Research Hospital, Clinic of Cardiology, Istanbul, TürkiyeObjective: This study investigated the modified Glasgow prognostic score (mGPS) to determine its predictive value and how it could be compared with various inflammatory markers, including C-reactive protein (CRP) to albumin ratio and neutrophil-to-lymphocyte ratio, for determining the extent and severity of coronary artery disease (CAD) in patients with non-ST-elevated myocardial infarction (NSTEMI). Methods: This study analyzed the cases of 295 patients with NSTEMI who had undergone coronary angiography. In an effort to determine the seriousness and scope of CAD in each patient, the Synergy between Percutaneous Coronary Intervention with Taxus and Cardiac Surgery (SYNTAX) score was calculated and then assessed. The study sample was divided into two separate groups based on the SYNTAX score: moderate to high SYNTAX (>22) and low SYNTAX (≤22). Results: There were 295 patients (23.1% female, 76.9% male) included in the research, with an average age being 61.2+-10.9 years, and the mean SYNTAX score being 7.3+-10.4 (range: 0-40). Those with a SYNTAX score >22 were observed to possess significantly higher levels of CRP, CRP/albumin ratio, and mean mGPS 1-2 ratios compared with those with a SYNTAX score ≤22 (all p<0.001). Smoking [odds ratio (OR): 3.341, 95% confidence interval (CI): 1.531-7.294; p=0.002], CRP/albumin ratio (OR: 4.958, 95% CI: 1.335-18.418; p=0.017), and mGPS score of 1-2 (OR: 3.121, 95% CI: 1.430-6.814; p=0.004) were independent factors used to help predict a high SYNTAX score. Conclusions: It seems possible to make use of the mGPS when estimating the degree and intricacies of CAD in patients with NSTEMI, as there appears to be a connection with higher SYNTAX scores.https://jag.journalagent.com/z4/download_fulltext.asp?pdir=medeniyet&un=MEDJ-32585modified glasgow prognostic score (mgps)syntax scorecoronary artery diseasenon-st-elevated myocardial infarction |
| spellingShingle | Ahmet KARADUMAN Cemalettin YILMAZ Mustafa Ferhat KETEN Ismail BALABAN Zeynep Esra GUNER Mehmet CELIK The Relationship Between the Modified Glasgow Prognostic and SYNTAX Scores in Patients with Non-ST Elevation Myocardial Infarction Medeniyet Medical Journal modified glasgow prognostic score (mgps) syntax score coronary artery disease non-st-elevated myocardial infarction |
| title | The Relationship Between the Modified Glasgow Prognostic and SYNTAX Scores in Patients with Non-ST Elevation Myocardial Infarction |
| title_full | The Relationship Between the Modified Glasgow Prognostic and SYNTAX Scores in Patients with Non-ST Elevation Myocardial Infarction |
| title_fullStr | The Relationship Between the Modified Glasgow Prognostic and SYNTAX Scores in Patients with Non-ST Elevation Myocardial Infarction |
| title_full_unstemmed | The Relationship Between the Modified Glasgow Prognostic and SYNTAX Scores in Patients with Non-ST Elevation Myocardial Infarction |
| title_short | The Relationship Between the Modified Glasgow Prognostic and SYNTAX Scores in Patients with Non-ST Elevation Myocardial Infarction |
| title_sort | relationship between the modified glasgow prognostic and syntax scores in patients with non st elevation myocardial infarction |
| topic | modified glasgow prognostic score (mgps) syntax score coronary artery disease non-st-elevated myocardial infarction |
| url | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=medeniyet&un=MEDJ-32585 |
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