Cissus quadrangularis: A comprehensive review as an emerging biomaterial for periodontal regeneration
Cissus quadrangularis (CQ) is known for its use as a folk medicine for pharmacological properties such as antimicrobial, antiulcer, anti-inflammatory, antitumor, antihemorrhagic, antiallergic, antidiabetic, and antioxidant properties. It is known for its significant role in fracture healing and bone...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2025-01-01
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| Series: | Journal of Oral Research and Review |
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| Online Access: | https://journals.lww.com/10.4103/jorr.jorr_27_24 |
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| author | H Nilofer Farjana G. Mohan Valiathan |
| author_facet | H Nilofer Farjana G. Mohan Valiathan |
| author_sort | H Nilofer Farjana |
| collection | DOAJ |
| description | Cissus quadrangularis (CQ) is known for its use as a folk medicine for pharmacological properties such as antimicrobial, antiulcer, anti-inflammatory, antitumor, antihemorrhagic, antiallergic, antidiabetic, and antioxidant properties. It is known for its significant role in fracture healing and bone regeneration. To date, it is safe without any adverse effects when used within normal limits. It contains phytoconstituents such as carbohydrates, phytosterols, flavonoids, triterpenoids, glycosides, tannins, saponins, proteins, Vitamin C, alkaloids, and calcium. The alveolar bone is the tooth-supporting apparatus comprising the alveolar bone proper, cortical bone, crestal alveolar bone, and trabecular bone. Periodontal disease is a polymicrobial host immune-mediated inflammatory disease that destroys supporting structures of the teeth. Periodontal regeneration regenerates the lost periodontal structures. It can be using bone grafts. Periodontal tissue engineering is surging in regenerative medicine. It is a triad that includes cells, scaffolds, and growth factors that help to form newly aligned functional periodontal structures. Plant medicine is an alternative medicine that overcomes the side effects of modern medicine. Plant extracts can be used as bioactive scaffolds for regeneration. CQ can differentiate human-derived mesenchymal stem cells into osteoblast and regenerate bone. This review elaborates on the use of CQ as a bioactive compound for periodontal regeneration. |
| format | Article |
| id | doaj-art-cc4ff6b734f249e5a7cce6a27dab6776 |
| institution | Kabale University |
| issn | 2249-4987 2394-2541 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Oral Research and Review |
| spelling | doaj-art-cc4ff6b734f249e5a7cce6a27dab67762025-02-06T07:07:49ZengWolters Kluwer Medknow PublicationsJournal of Oral Research and Review2249-49872394-25412025-01-01171879210.4103/jorr.jorr_27_24Cissus quadrangularis: A comprehensive review as an emerging biomaterial for periodontal regenerationH Nilofer FarjanaG. Mohan ValiathanCissus quadrangularis (CQ) is known for its use as a folk medicine for pharmacological properties such as antimicrobial, antiulcer, anti-inflammatory, antitumor, antihemorrhagic, antiallergic, antidiabetic, and antioxidant properties. It is known for its significant role in fracture healing and bone regeneration. To date, it is safe without any adverse effects when used within normal limits. It contains phytoconstituents such as carbohydrates, phytosterols, flavonoids, triterpenoids, glycosides, tannins, saponins, proteins, Vitamin C, alkaloids, and calcium. The alveolar bone is the tooth-supporting apparatus comprising the alveolar bone proper, cortical bone, crestal alveolar bone, and trabecular bone. Periodontal disease is a polymicrobial host immune-mediated inflammatory disease that destroys supporting structures of the teeth. Periodontal regeneration regenerates the lost periodontal structures. It can be using bone grafts. Periodontal tissue engineering is surging in regenerative medicine. It is a triad that includes cells, scaffolds, and growth factors that help to form newly aligned functional periodontal structures. Plant medicine is an alternative medicine that overcomes the side effects of modern medicine. Plant extracts can be used as bioactive scaffolds for regeneration. CQ can differentiate human-derived mesenchymal stem cells into osteoblast and regenerate bone. This review elaborates on the use of CQ as a bioactive compound for periodontal regeneration.https://journals.lww.com/10.4103/jorr.jorr_27_24cissus quadrangularisperiodontal regenerationplant medicinescaffold |
| spellingShingle | H Nilofer Farjana G. Mohan Valiathan Cissus quadrangularis: A comprehensive review as an emerging biomaterial for periodontal regeneration Journal of Oral Research and Review cissus quadrangularis periodontal regeneration plant medicine scaffold |
| title | Cissus quadrangularis: A comprehensive review as an emerging biomaterial for periodontal regeneration |
| title_full | Cissus quadrangularis: A comprehensive review as an emerging biomaterial for periodontal regeneration |
| title_fullStr | Cissus quadrangularis: A comprehensive review as an emerging biomaterial for periodontal regeneration |
| title_full_unstemmed | Cissus quadrangularis: A comprehensive review as an emerging biomaterial for periodontal regeneration |
| title_short | Cissus quadrangularis: A comprehensive review as an emerging biomaterial for periodontal regeneration |
| title_sort | cissus quadrangularis a comprehensive review as an emerging biomaterial for periodontal regeneration |
| topic | cissus quadrangularis periodontal regeneration plant medicine scaffold |
| url | https://journals.lww.com/10.4103/jorr.jorr_27_24 |
| work_keys_str_mv | AT hniloferfarjana cissusquadrangularisacomprehensivereviewasanemergingbiomaterialforperiodontalregeneration AT gmohanvaliathan cissusquadrangularisacomprehensivereviewasanemergingbiomaterialforperiodontalregeneration |