Use of Ketamine in Refractory Bronchospasm- A Study of 20 Cases
Objective: To study the effect of ketamine inpatients of severe wheezing due to bronchioli-tis who are refractory to the standard treatment.Methods: Prospective study including 104 chil-dren between 2 months to 2 years who pre-sented to us with severe wheezing due to bron-chiolitis. Initially they w...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Krishna Vishwa Vidyapeeth (Deemed to be University), Karad
2013-07-01
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| Series: | Journal of Krishna Institute of Medical Sciences University |
| Subjects: | |
| Online Access: | http://www.jkimsu.com/jkimsu-vol2no2/jkimsu%20vol%202%20no%202%20july%20-%20dec%202013%2060-68.pdf |
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| Summary: | Objective: To study the effect of ketamine inpatients of severe wheezing due to bronchioli-tis who are refractory to the standard treatment.Methods: Prospective study including 104 chil-dren between 2 months to 2 years who pre-sented to us with severe wheezing due to bron-chiolitis. Initially they were treated with humidi-fied oxygen and adrenaline nebulisation. Chil-dren with no response after 48 hours were givenintravenous ketamine as a bolus in dose of 1mg/kg. Patients were monitored with Uyanscore and oxygen saturation for 1 hour and thosewithout considerable improvement were givencontinuous infusion at 10 ìgm/kg/min.Results:104 patients were identified with severe wheez-ing due to bronchiolitis during study period. 84(81%) patients responded well to standardtreatment. 20 (19%) patients who did not im-prove were treated with ketamine. All patientsresponded to intravenous ketamine as bolus andshowed noticeable improvement in 1 hour withimprovement in scoring parameters. 14 (70%)patients had to be given infusion of ketamineand they were gradually weaned off the drip inan average of 15 hours. Conclusion: Use ofketamine in patients with severe wheezing dueto bronchiolitis who failed to respond to stan-dard treatment showed improvement which ob-viated the need for intubation and mechanicalventilation |
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| ISSN: | 2231-4261 |