A novel placement method of a calibration‐free pH capsule for continuous wireless measurement of intragastric pH in horses
Abstract Background Current methods to measure intragastric pH in horses have limitations. A wireless capsule has been designed for continuous esophageal pH monitoring in humans. Objectives To (1) determine the feasibility and describe the methodology of measuring intragastric pH wirelessly in horse...
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| Format: | Article |
| Language: | English |
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Wiley
2025-01-01
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| Series: | Journal of Veterinary Internal Medicine |
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| Online Access: | https://doi.org/10.1111/jvim.17273 |
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| author | Evelyn Hodgson Marthe Thirouin Pranav Narayanan Tallia‐Rume Romano Jessica Wise Stephanie Bond |
| author_facet | Evelyn Hodgson Marthe Thirouin Pranav Narayanan Tallia‐Rume Romano Jessica Wise Stephanie Bond |
| author_sort | Evelyn Hodgson |
| collection | DOAJ |
| description | Abstract Background Current methods to measure intragastric pH in horses have limitations. A wireless capsule has been designed for continuous esophageal pH monitoring in humans. Objectives To (1) determine the feasibility and describe the methodology of measuring intragastric pH wirelessly in horses; and (2) determine attachment duration of the capsules. Animals Eleven healthy adult horses. Methods Capsules were attached to squamous and glandular gastric mucosa under gastroscopic guidance, using suture loops and 1 to 4 hemostasis clips. pH was continuously recorded using a wireless recorder in both fed and fasted states. Gastroscopy was performed daily to assess capsule attachment and any mucosal damage. Data were analyzed using commercially available software. Values are reported as median (interquartile range). Results Capsules were successfully placed and data obtained in squamous (n = 11) and glandular (n = 7) regions. The overall duration of squamous capsule attachment was 27 hours (15‐32); 1 clip (n = 4) was 15 hours (11‐20), 2 clips (n = 2) was 20 hours (16‐23), 3 clips (n = 4) was 32 hours (30‐32), and 4 clips (n = 1) was 33 hours. The overall duration of glandular capsule attachment was 10 hours (8‐21); 1 clip (n = 2) was 11 hours (10‐13), 2 clips (n = 2) was 19 hours (14‐23), 3 clips (n = 2) was 7 hours (7‐8), and 4 clips (n = 1) was 158 hours. There was no substantial damage to the gastric mucosa as a consequence of attachment. Conclusions and Clinical Importance This novel technique enables the wireless measurement of intragastric pH in horses at known locations under fed and fasted conditions, providing a viable alternative for continuous monitoring in both research and clinical scenarios. |
| format | Article |
| id | doaj-art-cc226576b45249f18fbcfb8b3fd2896c |
| institution | Kabale University |
| issn | 0891-6640 1939-1676 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Veterinary Internal Medicine |
| spelling | doaj-art-cc226576b45249f18fbcfb8b3fd2896c2025-01-27T15:22:41ZengWileyJournal of Veterinary Internal Medicine0891-66401939-16762025-01-01391n/an/a10.1111/jvim.17273A novel placement method of a calibration‐free pH capsule for continuous wireless measurement of intragastric pH in horsesEvelyn Hodgson0Marthe Thirouin1Pranav Narayanan2Tallia‐Rume Romano3Jessica Wise4Stephanie Bond5School of Veterinary Science, Faculty of Science University of Queensland Gatton, Queensland 4343 AustraliaSchool of Veterinary Science, Faculty of Science University of Queensland Gatton, Queensland 4343 AustraliaSchool of Veterinary Science, Faculty of Science University of Queensland Gatton, Queensland 4343 AustraliaSchool of Veterinary Science, Faculty of Science University of Queensland Gatton, Queensland 4343 AustraliaSchool of Veterinary Science, Faculty of Science University of Queensland Gatton, Queensland 4343 AustraliaSchool of Veterinary Science, Faculty of Science University of Queensland Gatton, Queensland 4343 AustraliaAbstract Background Current methods to measure intragastric pH in horses have limitations. A wireless capsule has been designed for continuous esophageal pH monitoring in humans. Objectives To (1) determine the feasibility and describe the methodology of measuring intragastric pH wirelessly in horses; and (2) determine attachment duration of the capsules. Animals Eleven healthy adult horses. Methods Capsules were attached to squamous and glandular gastric mucosa under gastroscopic guidance, using suture loops and 1 to 4 hemostasis clips. pH was continuously recorded using a wireless recorder in both fed and fasted states. Gastroscopy was performed daily to assess capsule attachment and any mucosal damage. Data were analyzed using commercially available software. Values are reported as median (interquartile range). Results Capsules were successfully placed and data obtained in squamous (n = 11) and glandular (n = 7) regions. The overall duration of squamous capsule attachment was 27 hours (15‐32); 1 clip (n = 4) was 15 hours (11‐20), 2 clips (n = 2) was 20 hours (16‐23), 3 clips (n = 4) was 32 hours (30‐32), and 4 clips (n = 1) was 33 hours. The overall duration of glandular capsule attachment was 10 hours (8‐21); 1 clip (n = 2) was 11 hours (10‐13), 2 clips (n = 2) was 19 hours (14‐23), 3 clips (n = 2) was 7 hours (7‐8), and 4 clips (n = 1) was 158 hours. There was no substantial damage to the gastric mucosa as a consequence of attachment. Conclusions and Clinical Importance This novel technique enables the wireless measurement of intragastric pH in horses at known locations under fed and fasted conditions, providing a viable alternative for continuous monitoring in both research and clinical scenarios.https://doi.org/10.1111/jvim.17273EGGDEGUSequineESGDgastriculcers |
| spellingShingle | Evelyn Hodgson Marthe Thirouin Pranav Narayanan Tallia‐Rume Romano Jessica Wise Stephanie Bond A novel placement method of a calibration‐free pH capsule for continuous wireless measurement of intragastric pH in horses Journal of Veterinary Internal Medicine EGGD EGUS equine ESGD gastric ulcers |
| title | A novel placement method of a calibration‐free pH capsule for continuous wireless measurement of intragastric pH in horses |
| title_full | A novel placement method of a calibration‐free pH capsule for continuous wireless measurement of intragastric pH in horses |
| title_fullStr | A novel placement method of a calibration‐free pH capsule for continuous wireless measurement of intragastric pH in horses |
| title_full_unstemmed | A novel placement method of a calibration‐free pH capsule for continuous wireless measurement of intragastric pH in horses |
| title_short | A novel placement method of a calibration‐free pH capsule for continuous wireless measurement of intragastric pH in horses |
| title_sort | novel placement method of a calibration free ph capsule for continuous wireless measurement of intragastric ph in horses |
| topic | EGGD EGUS equine ESGD gastric ulcers |
| url | https://doi.org/10.1111/jvim.17273 |
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