MACC1 ablation suppresses the dedifferentiation process of non-CSCs in lung cancer through stabilizing KLF4

MACC1 ablation suppresses the dedifferentiation process of non-CSCs in lung cancer through stabilizing KLF4

Abstract Metastasis-associated in colon cancer-1 (MACC1) was identified as a new player in lung cancer development, and some stemness-related genes can be novel transcriptional targets of MACC1. Cancer stem cells (CSCs) are responsible for sustaining tumorigenesis and plasticity. Both CSCs and non-C...

Full description

Saved in:
Bibliographic Details
Main Authors: Zhuoshi Li, Shiqing Wang, Tao Guo, Xinyi Yan, Chaoqun Chen, Wenjing Zhang, Jinyao Zhao, Jinrui Zhang, Shilei Zhao, Yang Wang, Yangfan Qi, Chundong Gu
Format: Article
Language:English
Published: Nature Publishing Group 2024-12-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-024-02256-0
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items