Systemic Lupus Erythematosus with Multiple Autoimmune Disease Presented with Extensive Peripheral Gangrene
Systemic lupus erythematosus (SLE) is an autoimmune disease and can be associated with other autoimmune diseases. SLE usually presents with skin change and rarely presents with gangrene. SLE gangrene usually involves the digits of upper extremities. We report the first case of SLE associated with an...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Case Reports in Rheumatology |
| Online Access: | http://dx.doi.org/10.1155/2020/8278275 |
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| author | Tareq Z. Alzughayyar Jihad Samer Zalloum Mohammad N. Elqadi Sadi A. Abukhalaf Fawzy M. Abunejma Mohammed M. Y. Alkhanafsa Motasem H. M. Haif Firas Alqarajeh Mo’min R. Mesk Rami A. Misk |
| author_facet | Tareq Z. Alzughayyar Jihad Samer Zalloum Mohammad N. Elqadi Sadi A. Abukhalaf Fawzy M. Abunejma Mohammed M. Y. Alkhanafsa Motasem H. M. Haif Firas Alqarajeh Mo’min R. Mesk Rami A. Misk |
| author_sort | Tareq Z. Alzughayyar |
| collection | DOAJ |
| description | Systemic lupus erythematosus (SLE) is an autoimmune disease and can be associated with other autoimmune diseases. SLE usually presents with skin change and rarely presents with gangrene. SLE gangrene usually involves the digits of upper extremities. We report the first case of SLE associated with an extremely rare constellation of neuromyelitis Optica (NMO) and diabetes mellitus type 1, presented with a rare form of the SLE gangrene which involves bilateral lower extremities up to midlegs, a case that has not yet been reported in the literature. Although SLE gangrene may respond to immunosuppressants, it has a high risk of complications that can end up with amputations. |
| format | Article |
| id | doaj-art-cc10761d41a1438d9212973cff53264c |
| institution | Kabale University |
| issn | 2090-6889 2090-6897 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Rheumatology |
| spelling | doaj-art-cc10761d41a1438d9212973cff53264c2025-02-03T01:27:04ZengWileyCase Reports in Rheumatology2090-68892090-68972020-01-01202010.1155/2020/82782758278275Systemic Lupus Erythematosus with Multiple Autoimmune Disease Presented with Extensive Peripheral GangreneTareq Z. Alzughayyar0Jihad Samer Zalloum1Mohammad N. Elqadi2Sadi A. Abukhalaf3Fawzy M. Abunejma4Mohammed M. Y. Alkhanafsa5Motasem H. M. Haif6Firas Alqarajeh7Mo’min R. Mesk8Rami A. Misk9Al-Quds University, Faculty of Medicine, Jerusalem, State of PalestineAl-Quds University, Faculty of Medicine, Jerusalem, State of PalestineAl-Quds University, Faculty of Medicine, Jerusalem, State of PalestineAl-Quds University, Faculty of Medicine, Jerusalem, State of PalestinePediatric Rheumatologist, Al-Ahli Hospital, Hebron, State of PalestineAl-Quds University, Faculty of Medicine, Jerusalem, State of PalestineAl-Quds University, Faculty of Medicine, Jerusalem, State of PalestineAl-Quds University, Faculty of Medicine, Jerusalem, State of PalestineAl-Quds University, Faculty of Medicine, Jerusalem, State of PalestineAn-Najah National University, Faculty of Medicine & Health Sciences, Nablus, State of PalestineSystemic lupus erythematosus (SLE) is an autoimmune disease and can be associated with other autoimmune diseases. SLE usually presents with skin change and rarely presents with gangrene. SLE gangrene usually involves the digits of upper extremities. We report the first case of SLE associated with an extremely rare constellation of neuromyelitis Optica (NMO) and diabetes mellitus type 1, presented with a rare form of the SLE gangrene which involves bilateral lower extremities up to midlegs, a case that has not yet been reported in the literature. Although SLE gangrene may respond to immunosuppressants, it has a high risk of complications that can end up with amputations.http://dx.doi.org/10.1155/2020/8278275 |
| spellingShingle | Tareq Z. Alzughayyar Jihad Samer Zalloum Mohammad N. Elqadi Sadi A. Abukhalaf Fawzy M. Abunejma Mohammed M. Y. Alkhanafsa Motasem H. M. Haif Firas Alqarajeh Mo’min R. Mesk Rami A. Misk Systemic Lupus Erythematosus with Multiple Autoimmune Disease Presented with Extensive Peripheral Gangrene Case Reports in Rheumatology |
| title | Systemic Lupus Erythematosus with Multiple Autoimmune Disease Presented with Extensive Peripheral Gangrene |
| title_full | Systemic Lupus Erythematosus with Multiple Autoimmune Disease Presented with Extensive Peripheral Gangrene |
| title_fullStr | Systemic Lupus Erythematosus with Multiple Autoimmune Disease Presented with Extensive Peripheral Gangrene |
| title_full_unstemmed | Systemic Lupus Erythematosus with Multiple Autoimmune Disease Presented with Extensive Peripheral Gangrene |
| title_short | Systemic Lupus Erythematosus with Multiple Autoimmune Disease Presented with Extensive Peripheral Gangrene |
| title_sort | systemic lupus erythematosus with multiple autoimmune disease presented with extensive peripheral gangrene |
| url | http://dx.doi.org/10.1155/2020/8278275 |
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