Systemic Lupus Erythematosus with Multiple Autoimmune Disease Presented with Extensive Peripheral Gangrene

Systemic lupus erythematosus (SLE) is an autoimmune disease and can be associated with other autoimmune diseases. SLE usually presents with skin change and rarely presents with gangrene. SLE gangrene usually involves the digits of upper extremities. We report the first case of SLE associated with an...

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Main Authors: Tareq Z. Alzughayyar, Jihad Samer Zalloum, Mohammad N. Elqadi, Sadi A. Abukhalaf, Fawzy M. Abunejma, Mohammed M. Y. Alkhanafsa, Motasem H. M. Haif, Firas Alqarajeh, Mo’min R. Mesk, Rami A. Misk
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Case Reports in Rheumatology
Online Access:http://dx.doi.org/10.1155/2020/8278275
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Summary:Systemic lupus erythematosus (SLE) is an autoimmune disease and can be associated with other autoimmune diseases. SLE usually presents with skin change and rarely presents with gangrene. SLE gangrene usually involves the digits of upper extremities. We report the first case of SLE associated with an extremely rare constellation of neuromyelitis Optica (NMO) and diabetes mellitus type 1, presented with a rare form of the SLE gangrene which involves bilateral lower extremities up to midlegs, a case that has not yet been reported in the literature. Although SLE gangrene may respond to immunosuppressants, it has a high risk of complications that can end up with amputations.
ISSN:2090-6889
2090-6897