Black soldier fly larvae oil can partially replace fish oil in the diet of the juvenile mud crab (Scylla paramamosain)

An 8-week feeding trial was conducted to investigate the effects of replacing dietary fish oil (FO) with black soldier fly larval oil (BSFO) on growth performance, antioxidant and immune response, lipid metabolism and mitochondrial function of the juvenile mud crab. A total of 160 mud crabs (18.58 ±...

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Main Authors: Yuhang Yang, Tingting Zhu, Min Jin, Xiangkai Li, Shichao Xie, Yuhui Cui, Qicun Zhou
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-03-01
Series:Animal Nutrition
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Online Access:http://www.sciencedirect.com/science/article/pii/S2405654525000101
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author Yuhang Yang
Tingting Zhu
Min Jin
Xiangkai Li
Shichao Xie
Yuhui Cui
Qicun Zhou
author_facet Yuhang Yang
Tingting Zhu
Min Jin
Xiangkai Li
Shichao Xie
Yuhui Cui
Qicun Zhou
author_sort Yuhang Yang
collection DOAJ
description An 8-week feeding trial was conducted to investigate the effects of replacing dietary fish oil (FO) with black soldier fly larval oil (BSFO) on growth performance, antioxidant and immune response, lipid metabolism and mitochondrial function of the juvenile mud crab. A total of 160 mud crabs (18.58 ± 0.02 g) were randomly distributed into five treatments spread across 160 aquaria. There were 4 replicates per treatment and 8 crabs per replicate. The basal diet (Control) contained 3% fish oil and fish oil was replaced with BSFO at 25%, 50%, 75%, and 100% in the remaining four treatments. The results showed that when the proportion of BSFO replacing FO was less than 50%, there were no significant differences in percent weight gain (PWG), specific growth rate (SGR) and feed efficiency (FE) between the experimental and the control groups (P > 0.05); however, PWG and SGR decreased as the percentage of substitution increased from 50% to 100% (P < 0.01). When the percentage of substitution was less than 50%, the expression levels of genes related to lipid synthesis and catabolism were significantly up-regulated and down-regulated, respectively (P < 0.05). When 25% and 50% FO were replaced with BSFO, the antioxidant and immune responses enhanced (P < 0.05), and antioxidant and immune-related enzyme activities and metabolite concentrations in the hemolymph and hepatopancreas significantly increased (P < 0.05), and the concentrations of malondialdehyde (MDA) and protein carbonyl (PC), and the apoptosis index in the hepatopancreas significantly decreased (P < 0.05). Moreover, mitochondrial function indexes in the hepatopancreas, such as mitochondrial DNA copy number and expression levels of energy metabolism-related genes were significantly up-regulated (P < 0.05). Hepatopancreas mitochondria were more abundant in crabs fed diets with 25% and 50% replacement of FO with BSFO, while adenosine triphosphate content was the highest in 25% FO replacement group (P = 0.003). In summary, the results of the present study demonstrated that the replacement of FO with BSFO at less than 50% (i.e. in-feed BSFO level of 1.5%) did not negatively affect the growth performance of mud crabs, and could improve the antioxidant capacity, immune response, and enhance mitochondrial function.
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record_format Article
series Animal Nutrition
spelling doaj-art-cbd30e9034cc47d3a388b364e3c2da2e2025-08-20T02:54:15ZengKeAi Communications Co., Ltd.Animal Nutrition2405-65452025-03-012046948610.1016/j.aninu.2025.01.002Black soldier fly larvae oil can partially replace fish oil in the diet of the juvenile mud crab (Scylla paramamosain)Yuhang Yang0Tingting Zhu1Min Jin2Xiangkai Li3Shichao Xie4Yuhui Cui5Qicun Zhou6Laboratory of Fish and Shellfish Nutrition, School of Marine Sciences, Ningbo University, Ningbo 315211, China; Key Laboratory of Aquaculture Biotechnology Ministry of Education, Ningbo University, Ningbo 315211, China; Key Laboratory of Green Mariculture (Co-construction by Ministry and Province), Ministry of Agriculture and Rural, Ningbo 315211, China; Collaborative Innovation Center for Zhejiang Marine High-efficiency and Healthy Aquaculture, Ningbo 315211, ChinaLaboratory of Fish and Shellfish Nutrition, School of Marine Sciences, Ningbo University, Ningbo 315211, China; Key Laboratory of Aquaculture Biotechnology Ministry of Education, Ningbo University, Ningbo 315211, China; Key Laboratory of Green Mariculture (Co-construction by Ministry and Province), Ministry of Agriculture and Rural, Ningbo 315211, China; Collaborative Innovation Center for Zhejiang Marine High-efficiency and Healthy Aquaculture, Ningbo 315211, ChinaLaboratory of Fish and Shellfish Nutrition, School of Marine Sciences, Ningbo University, Ningbo 315211, China; Key Laboratory of Aquaculture Biotechnology Ministry of Education, Ningbo University, Ningbo 315211, China; Key Laboratory of Green Mariculture (Co-construction by Ministry and Province), Ministry of Agriculture and Rural, Ningbo 315211, China; Collaborative Innovation Center for Zhejiang Marine High-efficiency and Healthy Aquaculture, Ningbo 315211, China; Corresponding authors.Laboratory of Fish and Shellfish Nutrition, School of Marine Sciences, Ningbo University, Ningbo 315211, China; Key Laboratory of Aquaculture Biotechnology Ministry of Education, Ningbo University, Ningbo 315211, China; Key Laboratory of Green Mariculture (Co-construction by Ministry and Province), Ministry of Agriculture and Rural, Ningbo 315211, China; Collaborative Innovation Center for Zhejiang Marine High-efficiency and Healthy Aquaculture, Ningbo 315211, ChinaLaboratory of Fish and Shellfish Nutrition, School of Marine Sciences, Ningbo University, Ningbo 315211, China; Key Laboratory of Aquaculture Biotechnology Ministry of Education, Ningbo University, Ningbo 315211, China; Key Laboratory of Green Mariculture (Co-construction by Ministry and Province), Ministry of Agriculture and Rural, Ningbo 315211, China; Collaborative Innovation Center for Zhejiang Marine High-efficiency and Healthy Aquaculture, Ningbo 315211, ChinaLaboratory of Fish and Shellfish Nutrition, School of Marine Sciences, Ningbo University, Ningbo 315211, China; Key Laboratory of Aquaculture Biotechnology Ministry of Education, Ningbo University, Ningbo 315211, China; Key Laboratory of Green Mariculture (Co-construction by Ministry and Province), Ministry of Agriculture and Rural, Ningbo 315211, China; Collaborative Innovation Center for Zhejiang Marine High-efficiency and Healthy Aquaculture, Ningbo 315211, ChinaLaboratory of Fish and Shellfish Nutrition, School of Marine Sciences, Ningbo University, Ningbo 315211, China; Key Laboratory of Aquaculture Biotechnology Ministry of Education, Ningbo University, Ningbo 315211, China; Key Laboratory of Green Mariculture (Co-construction by Ministry and Province), Ministry of Agriculture and Rural, Ningbo 315211, China; Collaborative Innovation Center for Zhejiang Marine High-efficiency and Healthy Aquaculture, Ningbo 315211, China; Corresponding authors.An 8-week feeding trial was conducted to investigate the effects of replacing dietary fish oil (FO) with black soldier fly larval oil (BSFO) on growth performance, antioxidant and immune response, lipid metabolism and mitochondrial function of the juvenile mud crab. A total of 160 mud crabs (18.58 ± 0.02 g) were randomly distributed into five treatments spread across 160 aquaria. There were 4 replicates per treatment and 8 crabs per replicate. The basal diet (Control) contained 3% fish oil and fish oil was replaced with BSFO at 25%, 50%, 75%, and 100% in the remaining four treatments. The results showed that when the proportion of BSFO replacing FO was less than 50%, there were no significant differences in percent weight gain (PWG), specific growth rate (SGR) and feed efficiency (FE) between the experimental and the control groups (P > 0.05); however, PWG and SGR decreased as the percentage of substitution increased from 50% to 100% (P < 0.01). When the percentage of substitution was less than 50%, the expression levels of genes related to lipid synthesis and catabolism were significantly up-regulated and down-regulated, respectively (P < 0.05). When 25% and 50% FO were replaced with BSFO, the antioxidant and immune responses enhanced (P < 0.05), and antioxidant and immune-related enzyme activities and metabolite concentrations in the hemolymph and hepatopancreas significantly increased (P < 0.05), and the concentrations of malondialdehyde (MDA) and protein carbonyl (PC), and the apoptosis index in the hepatopancreas significantly decreased (P < 0.05). Moreover, mitochondrial function indexes in the hepatopancreas, such as mitochondrial DNA copy number and expression levels of energy metabolism-related genes were significantly up-regulated (P < 0.05). Hepatopancreas mitochondria were more abundant in crabs fed diets with 25% and 50% replacement of FO with BSFO, while adenosine triphosphate content was the highest in 25% FO replacement group (P = 0.003). In summary, the results of the present study demonstrated that the replacement of FO with BSFO at less than 50% (i.e. in-feed BSFO level of 1.5%) did not negatively affect the growth performance of mud crabs, and could improve the antioxidant capacity, immune response, and enhance mitochondrial function.http://www.sciencedirect.com/science/article/pii/S2405654525000101Scylla paramamosainBlack soldier fly larvae oilGrowthLipid metabolismMitochondrial function
spellingShingle Yuhang Yang
Tingting Zhu
Min Jin
Xiangkai Li
Shichao Xie
Yuhui Cui
Qicun Zhou
Black soldier fly larvae oil can partially replace fish oil in the diet of the juvenile mud crab (Scylla paramamosain)
Animal Nutrition
Scylla paramamosain
Black soldier fly larvae oil
Growth
Lipid metabolism
Mitochondrial function
title Black soldier fly larvae oil can partially replace fish oil in the diet of the juvenile mud crab (Scylla paramamosain)
title_full Black soldier fly larvae oil can partially replace fish oil in the diet of the juvenile mud crab (Scylla paramamosain)
title_fullStr Black soldier fly larvae oil can partially replace fish oil in the diet of the juvenile mud crab (Scylla paramamosain)
title_full_unstemmed Black soldier fly larvae oil can partially replace fish oil in the diet of the juvenile mud crab (Scylla paramamosain)
title_short Black soldier fly larvae oil can partially replace fish oil in the diet of the juvenile mud crab (Scylla paramamosain)
title_sort black soldier fly larvae oil can partially replace fish oil in the diet of the juvenile mud crab scylla paramamosain
topic Scylla paramamosain
Black soldier fly larvae oil
Growth
Lipid metabolism
Mitochondrial function
url http://www.sciencedirect.com/science/article/pii/S2405654525000101
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