Role of Vitamin D in Cardiometabolic Diseases
Vitamin D deficiency is a highly prevalent condition. Low vitamin D levels have long been associated with bone diseases, such as rickets in children and osteomalacia and osteoporosis in adults. However, it has become apparent in recent years that adequate vitamin D levels are also important for opti...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Journal of Diabetes Research |
| Online Access: | http://dx.doi.org/10.1155/2013/243934 |
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| _version_ | 1832548086966124544 |
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| author | Chaoxun Wang |
| author_facet | Chaoxun Wang |
| author_sort | Chaoxun Wang |
| collection | DOAJ |
| description | Vitamin D deficiency is a highly prevalent condition. Low vitamin D levels have long been associated with bone diseases, such as rickets in children and osteomalacia and osteoporosis in adults. However, it has become apparent in recent years that adequate vitamin D levels are also important for optimal functioning of many organs and tissues throughout the body, including the cardiovascular system. Evolving data indicate that vitamin D deficiency is associated with an increased risk of cardiovascular disease (CVD). Studies have shown that low vitamin D levels are associated with hypertension, diabetes, metabolic syndrome, left ventricular hypertrophy, and chronic vascular inflammation, all of which are risk factors for CVD. This paper reviews the definition and pathophysiology of vitamin D deficiency, clinical evidence linking vitamin D and CVD risk, diabetes and its complications, and metabolic syndrome. |
| format | Article |
| id | doaj-art-cbc733cfd10d4c539ecaf09b25b16b24 |
| institution | Kabale University |
| issn | 2314-6745 2314-6753 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Diabetes Research |
| spelling | doaj-art-cbc733cfd10d4c539ecaf09b25b16b242025-02-03T06:42:18ZengWileyJournal of Diabetes Research2314-67452314-67532013-01-01201310.1155/2013/243934243934Role of Vitamin D in Cardiometabolic DiseasesChaoxun Wang0Department of Endocrinology, Shanghai Pudong Hospital, 2800 Gongwei Road, Huinan Town, Pudong, Shanghai 201399, ChinaVitamin D deficiency is a highly prevalent condition. Low vitamin D levels have long been associated with bone diseases, such as rickets in children and osteomalacia and osteoporosis in adults. However, it has become apparent in recent years that adequate vitamin D levels are also important for optimal functioning of many organs and tissues throughout the body, including the cardiovascular system. Evolving data indicate that vitamin D deficiency is associated with an increased risk of cardiovascular disease (CVD). Studies have shown that low vitamin D levels are associated with hypertension, diabetes, metabolic syndrome, left ventricular hypertrophy, and chronic vascular inflammation, all of which are risk factors for CVD. This paper reviews the definition and pathophysiology of vitamin D deficiency, clinical evidence linking vitamin D and CVD risk, diabetes and its complications, and metabolic syndrome.http://dx.doi.org/10.1155/2013/243934 |
| spellingShingle | Chaoxun Wang Role of Vitamin D in Cardiometabolic Diseases Journal of Diabetes Research |
| title | Role of Vitamin D in Cardiometabolic Diseases |
| title_full | Role of Vitamin D in Cardiometabolic Diseases |
| title_fullStr | Role of Vitamin D in Cardiometabolic Diseases |
| title_full_unstemmed | Role of Vitamin D in Cardiometabolic Diseases |
| title_short | Role of Vitamin D in Cardiometabolic Diseases |
| title_sort | role of vitamin d in cardiometabolic diseases |
| url | http://dx.doi.org/10.1155/2013/243934 |
| work_keys_str_mv | AT chaoxunwang roleofvitamindincardiometabolicdiseases |