Lead, Cadmium, and Arsenic in Edible Tissues of Guinea Pigs Raised in the Central Andes of Peru: Potential Human Health Risk?

Toxic metals and metalloids food contamination is a source of health risks; this study evaluated lead (Pb), cadmium (Cd), and arsenic (AS) contamination in the meat, liver, kidneys, heart, and lungs of guinea pigs raised on a farm near a mini mineral concentrator and with pastures irrigated with was...

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Main Authors: Doris Chirinos-Peinado, Jorge Castro-Bedriñana, Fiorela Rivera-Parco, Elva Ríos-Ríos
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Veterinary Sciences
Subjects:
Online Access:https://www.mdpi.com/2306-7381/12/4/292
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author Doris Chirinos-Peinado
Jorge Castro-Bedriñana
Fiorela Rivera-Parco
Elva Ríos-Ríos
author_facet Doris Chirinos-Peinado
Jorge Castro-Bedriñana
Fiorela Rivera-Parco
Elva Ríos-Ríos
author_sort Doris Chirinos-Peinado
collection DOAJ
description Toxic metals and metalloids food contamination is a source of health risks; this study evaluated lead (Pb), cadmium (Cd), and arsenic (AS) contamination in the meat, liver, kidneys, heart, and lungs of guinea pigs raised on a farm near a mini mineral concentrator and with pastures irrigated with wastewater in the Central Andes of Peru. The risk of consuming these elements was estimated in the Peruvian population aged 2 to 85 years, whose consumption is 660 g/per capita/year. The quantification of Pb, Cd, and As was carried out via Inductively Coupled Plasma Atomic Emission Spectrometry. The heart had 3.3, 4.3, 7.3, and 81 times more Pb than the liver, lung, kidneys, and meat. The liver had 1.02, 2.22, 9.15, and 722.5 times more Cd than the kidneys, heart, lungs, and meat, respectively. The kidneys had 1.16 and 1.72 times more As than the liver and heart, respectively. The Target Hazard Quotient (TQH) and Hazard Index (HI) for Pb, Cd, and As, were <1 in the entire population, and there was no risk from their consumption. The cancer risk values found in the study are within the tolerated ranges. The findings expand the scientific basis for the safe and innocuous production of guinea pigs in the Central Andes of Peru and provide evidence to establish limits on water, soil, pastures, and agri-food products.
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spelling doaj-art-cbbb5c2529024c2c96e2a4bcd391c75c2025-08-20T02:18:10ZengMDPI AGVeterinary Sciences2306-73812025-03-0112429210.3390/vetsci12040292Lead, Cadmium, and Arsenic in Edible Tissues of Guinea Pigs Raised in the Central Andes of Peru: Potential Human Health Risk?Doris Chirinos-Peinado0Jorge Castro-Bedriñana1Fiorela Rivera-Parco2Elva Ríos-Ríos3Food and Nutritional Security Research Group, Universidad Nacional del Centro del Perú, Huancayo 12000, PeruFood and Nutritional Security Research Group, Universidad Nacional del Centro del Perú, Huancayo 12000, PeruFaculty of Zootechnics, Universidad Nacional del Centro del Perú, Huancayo 12000, PeruFaculty of Sciences, Universidad Nacional Agraria La Molina, Lima 15024, PeruToxic metals and metalloids food contamination is a source of health risks; this study evaluated lead (Pb), cadmium (Cd), and arsenic (AS) contamination in the meat, liver, kidneys, heart, and lungs of guinea pigs raised on a farm near a mini mineral concentrator and with pastures irrigated with wastewater in the Central Andes of Peru. The risk of consuming these elements was estimated in the Peruvian population aged 2 to 85 years, whose consumption is 660 g/per capita/year. The quantification of Pb, Cd, and As was carried out via Inductively Coupled Plasma Atomic Emission Spectrometry. The heart had 3.3, 4.3, 7.3, and 81 times more Pb than the liver, lung, kidneys, and meat. The liver had 1.02, 2.22, 9.15, and 722.5 times more Cd than the kidneys, heart, lungs, and meat, respectively. The kidneys had 1.16 and 1.72 times more As than the liver and heart, respectively. The Target Hazard Quotient (TQH) and Hazard Index (HI) for Pb, Cd, and As, were <1 in the entire population, and there was no risk from their consumption. The cancer risk values found in the study are within the tolerated ranges. The findings expand the scientific basis for the safe and innocuous production of guinea pigs in the Central Andes of Peru and provide evidence to establish limits on water, soil, pastures, and agri-food products.https://www.mdpi.com/2306-7381/12/4/292toxic metalstoxic metalloidsfood contaminationhealth risktarget hazard quotienthazard index
spellingShingle Doris Chirinos-Peinado
Jorge Castro-Bedriñana
Fiorela Rivera-Parco
Elva Ríos-Ríos
Lead, Cadmium, and Arsenic in Edible Tissues of Guinea Pigs Raised in the Central Andes of Peru: Potential Human Health Risk?
Veterinary Sciences
toxic metals
toxic metalloids
food contamination
health risk
target hazard quotient
hazard index
title Lead, Cadmium, and Arsenic in Edible Tissues of Guinea Pigs Raised in the Central Andes of Peru: Potential Human Health Risk?
title_full Lead, Cadmium, and Arsenic in Edible Tissues of Guinea Pigs Raised in the Central Andes of Peru: Potential Human Health Risk?
title_fullStr Lead, Cadmium, and Arsenic in Edible Tissues of Guinea Pigs Raised in the Central Andes of Peru: Potential Human Health Risk?
title_full_unstemmed Lead, Cadmium, and Arsenic in Edible Tissues of Guinea Pigs Raised in the Central Andes of Peru: Potential Human Health Risk?
title_short Lead, Cadmium, and Arsenic in Edible Tissues of Guinea Pigs Raised in the Central Andes of Peru: Potential Human Health Risk?
title_sort lead cadmium and arsenic in edible tissues of guinea pigs raised in the central andes of peru potential human health risk
topic toxic metals
toxic metalloids
food contamination
health risk
target hazard quotient
hazard index
url https://www.mdpi.com/2306-7381/12/4/292
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