Osteoradionecrosis of the mandible: Etiology, prevention, diagnosis and treatment

The treatment of head and neck cancer remains a challenge. Despite advances in surgical reconstructive techniques, most patients will require adjuvant therapy in the form of radiotherapy or chemo-radiotherapy to improve locoregional control. The short- and long term side effects of radiotherapy can...

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Main Authors: Rayatt Sukh, Mureau Marc, Hofer Stefan
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2007-12-01
Series:Indian Journal of Plastic Surgery
Subjects:
Online Access:http://www.ijps.org/article.asp?issn=0970-0358;year=2007;volume=40;issue=12;spage=65;epage=71;aulast=Rayatt
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author Rayatt Sukh
Mureau Marc
Hofer Stefan
author_facet Rayatt Sukh
Mureau Marc
Hofer Stefan
author_sort Rayatt Sukh
collection DOAJ
description The treatment of head and neck cancer remains a challenge. Despite advances in surgical reconstructive techniques, most patients will require adjuvant therapy in the form of radiotherapy or chemo-radiotherapy to improve locoregional control. The short- and long term side effects of radiotherapy can be difficult to treat. In this review the causative effects and pathogenesis of osteoradionecrosis of the mandible will be highlighted. In addition, preventive measures and clinical features of radiotherapy induced damage will be presented. Finally, medical and surgical management of osteoradionecrosis, as well as, reconstructive surgery of the mandible will be discussed. At the end of this paper the reader should have up to date knowledge concerning the etiology, prevention, diagnosis and treatment of patients with osteoradionecrosis of the mandible.
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series Indian Journal of Plastic Surgery
spelling doaj-art-cbb9930a48c84e6a9786d9c29cecb9c52025-08-20T03:23:37ZengThieme Medical and Scientific Publishers Pvt. Ltd.Indian Journal of Plastic Surgery0970-03582007-12-0140126571Osteoradionecrosis of the mandible: Etiology, prevention, diagnosis and treatmentRayatt SukhMureau MarcHofer StefanThe treatment of head and neck cancer remains a challenge. Despite advances in surgical reconstructive techniques, most patients will require adjuvant therapy in the form of radiotherapy or chemo-radiotherapy to improve locoregional control. The short- and long term side effects of radiotherapy can be difficult to treat. In this review the causative effects and pathogenesis of osteoradionecrosis of the mandible will be highlighted. In addition, preventive measures and clinical features of radiotherapy induced damage will be presented. Finally, medical and surgical management of osteoradionecrosis, as well as, reconstructive surgery of the mandible will be discussed. At the end of this paper the reader should have up to date knowledge concerning the etiology, prevention, diagnosis and treatment of patients with osteoradionecrosis of the mandible.http://www.ijps.org/article.asp?issn=0970-0358;year=2007;volume=40;issue=12;spage=65;epage=71;aulast=RayattFibula free flaphead and neck cancerhyperbaric oxygen therapymandibulamicrosurgeryosteoradionecrosisradiotherapy oral hygiene
spellingShingle Rayatt Sukh
Mureau Marc
Hofer Stefan
Osteoradionecrosis of the mandible: Etiology, prevention, diagnosis and treatment
Indian Journal of Plastic Surgery
Fibula free flap
head and neck cancer
hyperbaric oxygen therapy
mandibula
microsurgery
osteoradionecrosis
radiotherapy oral hygiene
title Osteoradionecrosis of the mandible: Etiology, prevention, diagnosis and treatment
title_full Osteoradionecrosis of the mandible: Etiology, prevention, diagnosis and treatment
title_fullStr Osteoradionecrosis of the mandible: Etiology, prevention, diagnosis and treatment
title_full_unstemmed Osteoradionecrosis of the mandible: Etiology, prevention, diagnosis and treatment
title_short Osteoradionecrosis of the mandible: Etiology, prevention, diagnosis and treatment
title_sort osteoradionecrosis of the mandible etiology prevention diagnosis and treatment
topic Fibula free flap
head and neck cancer
hyperbaric oxygen therapy
mandibula
microsurgery
osteoradionecrosis
radiotherapy oral hygiene
url http://www.ijps.org/article.asp?issn=0970-0358;year=2007;volume=40;issue=12;spage=65;epage=71;aulast=Rayatt
work_keys_str_mv AT rayattsukh osteoradionecrosisofthemandibleetiologypreventiondiagnosisandtreatment
AT mureaumarc osteoradionecrosisofthemandibleetiologypreventiondiagnosisandtreatment
AT hoferstefan osteoradionecrosisofthemandibleetiologypreventiondiagnosisandtreatment