An Ultrasound-Based Non-Invasive Blood Pressure Estimation Method Based on Optimal Vascular Wall Tracking Position

This study presents, for the first time, an ultrasound method combining focused and single plane wave transmissions to achieve single calibration, non-invasive, cuffless blood pressure monitoring. High-quality echo signals obtained from focused transmissions were first used to identify the optimal s...

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Main Authors: Liyuan Liu, Xingguang Geng, Fei Yao, Yitao Zhang, Haiying Zhang, Yunfeng Wang, Zhaoying Zheng
Format: Article
Language:English
Published: IEEE 2025-01-01
Series:IEEE Access
Subjects:
Online Access:https://ieeexplore.ieee.org/document/10819377/
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author Liyuan Liu
Xingguang Geng
Fei Yao
Yitao Zhang
Haiying Zhang
Yunfeng Wang
Zhaoying Zheng
author_facet Liyuan Liu
Xingguang Geng
Fei Yao
Yitao Zhang
Haiying Zhang
Yunfeng Wang
Zhaoying Zheng
author_sort Liyuan Liu
collection DOAJ
description This study presents, for the first time, an ultrasound method combining focused and single plane wave transmissions to achieve single calibration, non-invasive, cuffless blood pressure monitoring. High-quality echo signals obtained from focused transmissions were first used to identify the optimal segment of the radial artery wall. Then, single plane wave signals were utilized to track this segment frame-by-frame and calculate local pulse wave velocity (PWV). Finally, the M-K equation was applied to estimate systolic and diastolic blood pressures. To validate the effectiveness of the proposed algorithm, 25 volunteers participated in the study. Data were collected using both an oscillometric cuff-based blood pressure monitor and our ultrasound system in four states: morning, evening, pre-exercise, and post-exercise. A total of 300 sets of comparative data were obtained. The overall mean deviation for systolic blood pressure was <inline-formula> <tex-math notation="LaTeX">$2.2~\pm ~2.1$ </tex-math></inline-formula> mmHg, and for diastolic blood pressure, it was <inline-formula> <tex-math notation="LaTeX">$2.1~\pm ~2.2$ </tex-math></inline-formula> mmHg. To our knowledge, this is the first study to achieve real-time blood pressure calculation within seconds using a single-array ultrasound transducer. Compared to existing non-invasive continuous blood pressure monitoring methods, this approach is faster and provides more accurate vascular wall information. Significance: Combined with affordable hardware, this method holds significant potential for the development of wearable devices for real-time cardiovascular health monitoring.
format Article
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institution Kabale University
issn 2169-3536
language English
publishDate 2025-01-01
publisher IEEE
record_format Article
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spelling doaj-art-cbb22bb1d14849aa90c655ea3c5335472025-01-31T00:01:14ZengIEEEIEEE Access2169-35362025-01-0113171321714910.1109/ACCESS.2024.352461410819377An Ultrasound-Based Non-Invasive Blood Pressure Estimation Method Based on Optimal Vascular Wall Tracking PositionLiyuan Liu0https://orcid.org/0009-0003-0784-6025Xingguang Geng1https://orcid.org/0000-0002-7705-1936Fei Yao2Yitao Zhang3https://orcid.org/0000-0002-6022-7720Haiying Zhang4https://orcid.org/0000-0003-1911-7957Yunfeng Wang5https://orcid.org/0000-0003-2738-8706Zhaoying Zheng6Institute of Microelectronics of the Chinese Academy of Sciences, Beijing, ChinaInstitute of Microelectronics of the Chinese Academy of Sciences, Beijing, ChinaInstitute of Microelectronics of the Chinese Academy of Sciences, Beijing, ChinaInstitute of Microelectronics of the Chinese Academy of Sciences, Beijing, ChinaInstitute of Microelectronics of the Chinese Academy of Sciences, Beijing, ChinaInstitute of Microelectronics of the Chinese Academy of Sciences, Beijing, ChinaChina Academy of Chinese Medical Sciences, Institute of Basic Theory for Chinese Medicine, Beijing, ChinaThis study presents, for the first time, an ultrasound method combining focused and single plane wave transmissions to achieve single calibration, non-invasive, cuffless blood pressure monitoring. High-quality echo signals obtained from focused transmissions were first used to identify the optimal segment of the radial artery wall. Then, single plane wave signals were utilized to track this segment frame-by-frame and calculate local pulse wave velocity (PWV). Finally, the M-K equation was applied to estimate systolic and diastolic blood pressures. To validate the effectiveness of the proposed algorithm, 25 volunteers participated in the study. Data were collected using both an oscillometric cuff-based blood pressure monitor and our ultrasound system in four states: morning, evening, pre-exercise, and post-exercise. A total of 300 sets of comparative data were obtained. The overall mean deviation for systolic blood pressure was <inline-formula> <tex-math notation="LaTeX">$2.2~\pm ~2.1$ </tex-math></inline-formula> mmHg, and for diastolic blood pressure, it was <inline-formula> <tex-math notation="LaTeX">$2.1~\pm ~2.2$ </tex-math></inline-formula> mmHg. To our knowledge, this is the first study to achieve real-time blood pressure calculation within seconds using a single-array ultrasound transducer. Compared to existing non-invasive continuous blood pressure monitoring methods, this approach is faster and provides more accurate vascular wall information. Significance: Combined with affordable hardware, this method holds significant potential for the development of wearable devices for real-time cardiovascular health monitoring.https://ieeexplore.ieee.org/document/10819377/Array ultrasound signalradial artery wall target regionK-meansCannycuffless continuousultrasound blood pressure estimation
spellingShingle Liyuan Liu
Xingguang Geng
Fei Yao
Yitao Zhang
Haiying Zhang
Yunfeng Wang
Zhaoying Zheng
An Ultrasound-Based Non-Invasive Blood Pressure Estimation Method Based on Optimal Vascular Wall Tracking Position
IEEE Access
Array ultrasound signal
radial artery wall target region
K-means
Canny
cuffless continuous
ultrasound blood pressure estimation
title An Ultrasound-Based Non-Invasive Blood Pressure Estimation Method Based on Optimal Vascular Wall Tracking Position
title_full An Ultrasound-Based Non-Invasive Blood Pressure Estimation Method Based on Optimal Vascular Wall Tracking Position
title_fullStr An Ultrasound-Based Non-Invasive Blood Pressure Estimation Method Based on Optimal Vascular Wall Tracking Position
title_full_unstemmed An Ultrasound-Based Non-Invasive Blood Pressure Estimation Method Based on Optimal Vascular Wall Tracking Position
title_short An Ultrasound-Based Non-Invasive Blood Pressure Estimation Method Based on Optimal Vascular Wall Tracking Position
title_sort ultrasound based non invasive blood pressure estimation method based on optimal vascular wall tracking position
topic Array ultrasound signal
radial artery wall target region
K-means
Canny
cuffless continuous
ultrasound blood pressure estimation
url https://ieeexplore.ieee.org/document/10819377/
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