Complicated Dengue Fever and Its Treatment Dilemmas: A Single-Center Experience in Sri Lanka
Dengue is an arboviral infection that affects humanscausing significant morbidity and mortality in tropical countries. Our first patient who had diabetes presented with shock and was managed as dengue hemorrhagic fever with superadded sepsis which required noradrenalin plus broad-spectrum intravenou...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2021-01-01
|
| Series: | Case Reports in Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/2021/8854282 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832568526412447744 |
|---|---|
| author | D. K. Jayaweera S. Subasinghe R. F. De Silva W. A. H. P. Sanjeewa K. P. Jayawickreme |
| author_facet | D. K. Jayaweera S. Subasinghe R. F. De Silva W. A. H. P. Sanjeewa K. P. Jayawickreme |
| author_sort | D. K. Jayaweera |
| collection | DOAJ |
| description | Dengue is an arboviral infection that affects humanscausing significant morbidity and mortality in tropical countries. Our first patient who had diabetes presented with shock and was managed as dengue hemorrhagic fever with superadded sepsis which required noradrenalin plus broad-spectrum intravenous antibiotics. The second patient developed severe bradycardia during the ascending limb of the critical phase with hemodynamic stability, which recovered on discharge. Third patient presented with severe and rapid leaking; we used intravenous albumin as an alternative colloid with good outcome. The fourth patient was a pregnant mother at term, and she went into spontaneous labor during the latter half of the critical phase. The fifth patient developed dengue hemorrhagic fever complicated with probable haemophagocytic lymphohistiocytosis. She was treated with intravenous steroids andimmunoglobulin, yet succumbed on day 7. Conclusion. Dengue is an extremely challenging and dynamic disease, which can lead to many unusual complications.A high index of suspicion is key to diagnose and treat promptly. |
| format | Article |
| id | doaj-art-cbab96383169417cbe4b81aceec06be2 |
| institution | Kabale University |
| issn | 2090-6625 2090-6633 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Infectious Diseases |
| spelling | doaj-art-cbab96383169417cbe4b81aceec06be22025-02-03T00:58:55ZengWileyCase Reports in Infectious Diseases2090-66252090-66332021-01-01202110.1155/2021/88542828854282Complicated Dengue Fever and Its Treatment Dilemmas: A Single-Center Experience in Sri LankaD. K. Jayaweera0S. Subasinghe1R. F. De Silva2W. A. H. P. Sanjeewa3K. P. Jayawickreme4Registrar in Medicine Ward 17 Sri Jayewardenepura General Hospital Sri Lanka, Sri Jayawardenepura Kotte, Sri LankaRegistrar in Medicine Ward 17 Sri Jayewardenepura General Hospital Sri Lanka, Sri Jayawardenepura Kotte, Sri LankaRegistrar in Medicine Ward 17 Sri Jayewardenepura General Hospital Sri Lanka, Sri Jayawardenepura Kotte, Sri LankaRegistrar in Medicine Ward 17 Sri Jayewardenepura General Hospital Sri Lanka, Sri Jayawardenepura Kotte, Sri LankaRegistrar in Medicine Ward 17 Sri Jayewardenepura General Hospital Sri Lanka, Sri Jayawardenepura Kotte, Sri LankaDengue is an arboviral infection that affects humanscausing significant morbidity and mortality in tropical countries. Our first patient who had diabetes presented with shock and was managed as dengue hemorrhagic fever with superadded sepsis which required noradrenalin plus broad-spectrum intravenous antibiotics. The second patient developed severe bradycardia during the ascending limb of the critical phase with hemodynamic stability, which recovered on discharge. Third patient presented with severe and rapid leaking; we used intravenous albumin as an alternative colloid with good outcome. The fourth patient was a pregnant mother at term, and she went into spontaneous labor during the latter half of the critical phase. The fifth patient developed dengue hemorrhagic fever complicated with probable haemophagocytic lymphohistiocytosis. She was treated with intravenous steroids andimmunoglobulin, yet succumbed on day 7. Conclusion. Dengue is an extremely challenging and dynamic disease, which can lead to many unusual complications.A high index of suspicion is key to diagnose and treat promptly.http://dx.doi.org/10.1155/2021/8854282 |
| spellingShingle | D. K. Jayaweera S. Subasinghe R. F. De Silva W. A. H. P. Sanjeewa K. P. Jayawickreme Complicated Dengue Fever and Its Treatment Dilemmas: A Single-Center Experience in Sri Lanka Case Reports in Infectious Diseases |
| title | Complicated Dengue Fever and Its Treatment Dilemmas: A Single-Center Experience in Sri Lanka |
| title_full | Complicated Dengue Fever and Its Treatment Dilemmas: A Single-Center Experience in Sri Lanka |
| title_fullStr | Complicated Dengue Fever and Its Treatment Dilemmas: A Single-Center Experience in Sri Lanka |
| title_full_unstemmed | Complicated Dengue Fever and Its Treatment Dilemmas: A Single-Center Experience in Sri Lanka |
| title_short | Complicated Dengue Fever and Its Treatment Dilemmas: A Single-Center Experience in Sri Lanka |
| title_sort | complicated dengue fever and its treatment dilemmas a single center experience in sri lanka |
| url | http://dx.doi.org/10.1155/2021/8854282 |
| work_keys_str_mv | AT dkjayaweera complicateddenguefeveranditstreatmentdilemmasasinglecenterexperienceinsrilanka AT ssubasinghe complicateddenguefeveranditstreatmentdilemmasasinglecenterexperienceinsrilanka AT rfdesilva complicateddenguefeveranditstreatmentdilemmasasinglecenterexperienceinsrilanka AT wahpsanjeewa complicateddenguefeveranditstreatmentdilemmasasinglecenterexperienceinsrilanka AT kpjayawickreme complicateddenguefeveranditstreatmentdilemmasasinglecenterexperienceinsrilanka |