Coronary Heart Disease in Postmenopausal Women with Type II Diabetes Mellitus and the Impact of Estrogen Replacement Therapy: A Narrative Review
Coronary heart disease is the main cause of death in postmenopausal women (PMW); moreover its mortality exceeds those for breast cancer in women at all ages. Type II diabetes mellitus is a major cardiovascular risk factor and there is some evidence that the risk conferred by diabetes is greater in w...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2014-01-01
|
| Series: | International Journal of Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2014/413920 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832554522120028160 |
|---|---|
| author | Marouane Boukhris Salvatore Davide Tomasello Francesco Marzà Sonia Bregante Francesca Romana Pluchinotta Alfredo Ruggero Galassi |
| author_facet | Marouane Boukhris Salvatore Davide Tomasello Francesco Marzà Sonia Bregante Francesca Romana Pluchinotta Alfredo Ruggero Galassi |
| author_sort | Marouane Boukhris |
| collection | DOAJ |
| description | Coronary heart disease is the main cause of death in postmenopausal women (PMW); moreover its mortality exceeds those for breast cancer in women at all ages. Type II diabetes mellitus is a major cardiovascular risk factor and there is some evidence that the risk conferred by diabetes is greater in women than in men. It was established that the deficiency of endogenous estrogens promotes the atherosclerosis process. However, the impact of estrogen replacement therapy (ERT) on cardiovascular prevention remains controversial. Some authors strongly recommend it, whereas others revealed a concerning trend toward harm. This review tries to underlines the different components of cardiovascular risk in diabetic PMW and to define the place of ERT. |
| format | Article |
| id | doaj-art-cb79d7fe2a7f423a8343fb5a0d194187 |
| institution | Kabale University |
| issn | 1687-8337 1687-8345 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Endocrinology |
| spelling | doaj-art-cb79d7fe2a7f423a8343fb5a0d1941872025-02-03T05:51:18ZengWileyInternational Journal of Endocrinology1687-83371687-83452014-01-01201410.1155/2014/413920413920Coronary Heart Disease in Postmenopausal Women with Type II Diabetes Mellitus and the Impact of Estrogen Replacement Therapy: A Narrative ReviewMarouane Boukhris0Salvatore Davide Tomasello1Francesco Marzà2Sonia Bregante3Francesca Romana Pluchinotta4Alfredo Ruggero Galassi5Department of Medical Sciences and Pediatrics, Catheterization Laboratory and Cardiovascular Interventional Unit, Cannizzaro Hospital, University of Catania, Via Messina 829, 95126 Catania, ItalyDepartment of Medical Sciences and Pediatrics, Catheterization Laboratory and Cardiovascular Interventional Unit, Cannizzaro Hospital, University of Catania, Via Messina 829, 95126 Catania, ItalyDepartment of Medical Sciences and Pediatrics, Catheterization Laboratory and Cardiovascular Interventional Unit, Cannizzaro Hospital, University of Catania, Via Messina 829, 95126 Catania, ItalyIRCCS Policlinico S. Donato, Via Morandi 30, 20097 Milano, ItalyIRCCS Policlinico S. Donato, Via Morandi 30, 20097 Milano, ItalyDepartment of Medical Sciences and Pediatrics, Catheterization Laboratory and Cardiovascular Interventional Unit, Cannizzaro Hospital, University of Catania, Via Messina 829, 95126 Catania, ItalyCoronary heart disease is the main cause of death in postmenopausal women (PMW); moreover its mortality exceeds those for breast cancer in women at all ages. Type II diabetes mellitus is a major cardiovascular risk factor and there is some evidence that the risk conferred by diabetes is greater in women than in men. It was established that the deficiency of endogenous estrogens promotes the atherosclerosis process. However, the impact of estrogen replacement therapy (ERT) on cardiovascular prevention remains controversial. Some authors strongly recommend it, whereas others revealed a concerning trend toward harm. This review tries to underlines the different components of cardiovascular risk in diabetic PMW and to define the place of ERT.http://dx.doi.org/10.1155/2014/413920 |
| spellingShingle | Marouane Boukhris Salvatore Davide Tomasello Francesco Marzà Sonia Bregante Francesca Romana Pluchinotta Alfredo Ruggero Galassi Coronary Heart Disease in Postmenopausal Women with Type II Diabetes Mellitus and the Impact of Estrogen Replacement Therapy: A Narrative Review International Journal of Endocrinology |
| title | Coronary Heart Disease in Postmenopausal Women with Type II Diabetes Mellitus and the Impact of Estrogen Replacement Therapy: A Narrative Review |
| title_full | Coronary Heart Disease in Postmenopausal Women with Type II Diabetes Mellitus and the Impact of Estrogen Replacement Therapy: A Narrative Review |
| title_fullStr | Coronary Heart Disease in Postmenopausal Women with Type II Diabetes Mellitus and the Impact of Estrogen Replacement Therapy: A Narrative Review |
| title_full_unstemmed | Coronary Heart Disease in Postmenopausal Women with Type II Diabetes Mellitus and the Impact of Estrogen Replacement Therapy: A Narrative Review |
| title_short | Coronary Heart Disease in Postmenopausal Women with Type II Diabetes Mellitus and the Impact of Estrogen Replacement Therapy: A Narrative Review |
| title_sort | coronary heart disease in postmenopausal women with type ii diabetes mellitus and the impact of estrogen replacement therapy a narrative review |
| url | http://dx.doi.org/10.1155/2014/413920 |
| work_keys_str_mv | AT marouaneboukhris coronaryheartdiseaseinpostmenopausalwomenwithtypeiidiabetesmellitusandtheimpactofestrogenreplacementtherapyanarrativereview AT salvatoredavidetomasello coronaryheartdiseaseinpostmenopausalwomenwithtypeiidiabetesmellitusandtheimpactofestrogenreplacementtherapyanarrativereview AT francescomarza coronaryheartdiseaseinpostmenopausalwomenwithtypeiidiabetesmellitusandtheimpactofestrogenreplacementtherapyanarrativereview AT soniabregante coronaryheartdiseaseinpostmenopausalwomenwithtypeiidiabetesmellitusandtheimpactofestrogenreplacementtherapyanarrativereview AT francescaromanapluchinotta coronaryheartdiseaseinpostmenopausalwomenwithtypeiidiabetesmellitusandtheimpactofestrogenreplacementtherapyanarrativereview AT alfredoruggerogalassi coronaryheartdiseaseinpostmenopausalwomenwithtypeiidiabetesmellitusandtheimpactofestrogenreplacementtherapyanarrativereview |