Structural insights into HIV-2 CA lattice formation and FG-pocket binding revealed by single-particle cryo-EM

Structural insights into HIV-2 CA lattice formation and FG-pocket binding revealed by single-particle cryo-EM

Summary: One of the striking features of human immunodeficiency virus (HIV) is the capsid, a fullerene cone comprised of pleomorphic capsid protein (CA) that shields the viral genome and recruits cofactors. Despite significant advances in understanding the mechanisms of HIV-1 CA assembly and host fa...

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Bibliographic Details
Main Authors: Matthew Cook, Christian Freniere, Chunxiang Wu, Faith Lozano, Yong Xiong
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Cell Reports
Subjects:
CP: Microbiology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725000166
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