Acute Brucellosis Presenting with Bleeding Tendency due to Isolated Severe Thrombocytopenia
Mild anemia and leukopenia are the most common hematologic findings in the course of acute brucellosis. Severe form of thrombocytopenia is less frequently reported. We describe a case of acute brucellosis in a 20-year-old man, who presented with fever, purpuric skin lesions, epistaxis, and hematuria...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Case Reports in Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/2018/7867435 |
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| author | M. Aon T. Al-Enezi |
| author_facet | M. Aon T. Al-Enezi |
| author_sort | M. Aon |
| collection | DOAJ |
| description | Mild anemia and leukopenia are the most common hematologic findings in the course of acute brucellosis. Severe form of thrombocytopenia is less frequently reported. We describe a case of acute brucellosis in a 20-year-old man, who presented with fever, purpuric skin lesions, epistaxis, and hematuria. The absolute platelet count was 2 × 109/L. The patient was diagnosed as suffering from brucellosis on the basis of a strongly positive serologic reaction and was treated with antibiotics and a short course of corticosteroids, with a rapid rise in platelet count. Brucella infection can cause immune-mediated thrombocytopenia that is reversible after appropriate antimicrobial therapy and steroid treatment. |
| format | Article |
| id | doaj-art-cb303030c0a045af80806b761dbc1d84 |
| institution | Kabale University |
| issn | 2090-6625 2090-6633 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Infectious Diseases |
| spelling | doaj-art-cb303030c0a045af80806b761dbc1d842025-02-03T01:12:08ZengWileyCase Reports in Infectious Diseases2090-66252090-66332018-01-01201810.1155/2018/78674357867435Acute Brucellosis Presenting with Bleeding Tendency due to Isolated Severe ThrombocytopeniaM. Aon0T. Al-Enezi1Department of Medicine, Faculty of Medicine, Cairo University, Giza, EgyptDepartment of Medicine, Jahra Hospital, Al-Jahra, KuwaitMild anemia and leukopenia are the most common hematologic findings in the course of acute brucellosis. Severe form of thrombocytopenia is less frequently reported. We describe a case of acute brucellosis in a 20-year-old man, who presented with fever, purpuric skin lesions, epistaxis, and hematuria. The absolute platelet count was 2 × 109/L. The patient was diagnosed as suffering from brucellosis on the basis of a strongly positive serologic reaction and was treated with antibiotics and a short course of corticosteroids, with a rapid rise in platelet count. Brucella infection can cause immune-mediated thrombocytopenia that is reversible after appropriate antimicrobial therapy and steroid treatment.http://dx.doi.org/10.1155/2018/7867435 |
| spellingShingle | M. Aon T. Al-Enezi Acute Brucellosis Presenting with Bleeding Tendency due to Isolated Severe Thrombocytopenia Case Reports in Infectious Diseases |
| title | Acute Brucellosis Presenting with Bleeding Tendency due to Isolated Severe Thrombocytopenia |
| title_full | Acute Brucellosis Presenting with Bleeding Tendency due to Isolated Severe Thrombocytopenia |
| title_fullStr | Acute Brucellosis Presenting with Bleeding Tendency due to Isolated Severe Thrombocytopenia |
| title_full_unstemmed | Acute Brucellosis Presenting with Bleeding Tendency due to Isolated Severe Thrombocytopenia |
| title_short | Acute Brucellosis Presenting with Bleeding Tendency due to Isolated Severe Thrombocytopenia |
| title_sort | acute brucellosis presenting with bleeding tendency due to isolated severe thrombocytopenia |
| url | http://dx.doi.org/10.1155/2018/7867435 |
| work_keys_str_mv | AT maon acutebrucellosispresentingwithbleedingtendencyduetoisolatedseverethrombocytopenia AT talenezi acutebrucellosispresentingwithbleedingtendencyduetoisolatedseverethrombocytopenia |