H. capsulatum: A Not-So-Benign Cause of Pericarditis
The common causes of pericarditis and its course are benign in the majority of cases. Thus, further testing is usually not pursued and treatment for a presumptive viral etiology with nonsteroidal agents and steroids has been an accepted strategy. We present a patient with pericarditis who was unresp...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Case Reports in Cardiology |
| Online Access: | http://dx.doi.org/10.1155/2017/3626917 |
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| author | Paolo K. Soriano Muhammad Iqbal Shakthishri Kandaswamy Sami Akram Abhishek Kulkarni Tamer Hudali |
| author_facet | Paolo K. Soriano Muhammad Iqbal Shakthishri Kandaswamy Sami Akram Abhishek Kulkarni Tamer Hudali |
| author_sort | Paolo K. Soriano |
| collection | DOAJ |
| description | The common causes of pericarditis and its course are benign in the majority of cases. Thus, further testing is usually not pursued and treatment for a presumptive viral etiology with nonsteroidal agents and steroids has been an accepted strategy. We present a patient with pericarditis who was unresponsive to first-line therapy and was subsequently found to have necrotizing granulomas of the pericardium with extensive adhesions and fungal elements seen on tissue biopsy. Serologic testing confirms active H. capsulatum infection, and he responded well to Itraconazole treatment. In patients with pericarditis who fail standard therapy with NSAIDs and steroids, it is suggested that they undergo thorough evaluation and that histoplasmosis be considered as an etiology, especially in endemic regions. |
| format | Article |
| id | doaj-art-cb17333595d14827b683ede7d2768f00 |
| institution | Kabale University |
| issn | 2090-6404 2090-6412 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Cardiology |
| spelling | doaj-art-cb17333595d14827b683ede7d2768f002025-02-03T05:51:25ZengWileyCase Reports in Cardiology2090-64042090-64122017-01-01201710.1155/2017/36269173626917H. capsulatum: A Not-So-Benign Cause of PericarditisPaolo K. Soriano0Muhammad Iqbal1Shakthishri Kandaswamy2Sami Akram3Abhishek Kulkarni4Tamer Hudali5Department of Internal Medicine, Southern Illinois University, 751 N Rutledge, Springfield, IL 62702, USADepartment of Internal Medicine, Southern Illinois University, 751 N Rutledge, Springfield, IL 62702, USADepartment of Internal Medicine, Southern Illinois University, 751 N Rutledge, Springfield, IL 62702, USAInfectious Disease, Southern Illinois University, 751 N Rutledge, Springfield, IL 62702, USADivision of Cardiology, Southern Illinois University, 751 N Rutledge, Springfield, IL 62702, USAClinical Internal Medicine, Southern Illinois University, 751 N Rutledge, Springfield, IL 62702, USAThe common causes of pericarditis and its course are benign in the majority of cases. Thus, further testing is usually not pursued and treatment for a presumptive viral etiology with nonsteroidal agents and steroids has been an accepted strategy. We present a patient with pericarditis who was unresponsive to first-line therapy and was subsequently found to have necrotizing granulomas of the pericardium with extensive adhesions and fungal elements seen on tissue biopsy. Serologic testing confirms active H. capsulatum infection, and he responded well to Itraconazole treatment. In patients with pericarditis who fail standard therapy with NSAIDs and steroids, it is suggested that they undergo thorough evaluation and that histoplasmosis be considered as an etiology, especially in endemic regions.http://dx.doi.org/10.1155/2017/3626917 |
| spellingShingle | Paolo K. Soriano Muhammad Iqbal Shakthishri Kandaswamy Sami Akram Abhishek Kulkarni Tamer Hudali H. capsulatum: A Not-So-Benign Cause of Pericarditis Case Reports in Cardiology |
| title | H. capsulatum: A Not-So-Benign Cause of Pericarditis |
| title_full | H. capsulatum: A Not-So-Benign Cause of Pericarditis |
| title_fullStr | H. capsulatum: A Not-So-Benign Cause of Pericarditis |
| title_full_unstemmed | H. capsulatum: A Not-So-Benign Cause of Pericarditis |
| title_short | H. capsulatum: A Not-So-Benign Cause of Pericarditis |
| title_sort | h capsulatum a not so benign cause of pericarditis |
| url | http://dx.doi.org/10.1155/2017/3626917 |
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