Efficacy and safety of combining re-irradiation with bevacizumab compared to bevacizumab alone in the management of recurrent high-grade gliomas: a meta-analysis and systematic review

Efficacy and safety of combining re-irradiation with bevacizumab compared to bevacizumab alone in the management of recurrent high-grade gliomas: a meta-analysis and systematic review

Background: There is currently no established standard of care for recurrent glioblastoma (GBM). Re-irradiation (re-RT) and Bevacizumab (BEV) are both used in salvage treatment, but their combined efficacy remains uncertain. Objectives: To evaluate whether combining re-irradiation with BEV improves...

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Main Authors: Ali Hammed, Almonzer Al-Qiami, Ali Hasan, Gregor Richter, Asmaa Zakria Alnajjar, Josef Rosenbauer, Karel Kostev, Omar Ismail, Veit Braun, Christian Tanislav
Format: Article
Language:English
Published: SAGE Publishing 2025-06-01
Series:Therapeutic Advances in Neurological Disorders
Online Access:https://doi.org/10.1177/17562864251343574
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