Computational analysis of the functional impact of MHC-II-expressing triple-negative breast cancer

Computational analysis of the functional impact of MHC-II-expressing triple-negative breast cancer

The tumor microenvironment (TME) plays a crucial role in tumor progression and immunoregulation. Major histocompatibility complex class II (MHC-II) is essential for immune surveillance within the TME. While MHC-II genes are typically expressed by professional antigen-presenting cells, they are also...

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Bibliographic Details
Main Authors: Yang Cui, Weihang Zhang, Xin Zeng, Yitao Yang, Sung-Joon Park, Kenta Nakai
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Immunology
Subjects:
breast cancer
machine learning
MHC-II pathway
multi-omics data integration
tumor microenvironment
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1497251/full
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