A Case of Coronary Vasospasm after Repeat Rituximab Infusion
Coronary artery vasospasm (CAV) can be triggered by medication reactions. CAV occurring after multiple exposures to rituximab has not been previously described. A 61-year-old woman with no cardiac risk factors was treated with the sixth cycle of gemcitabine, cisplatin, dexamethasone, and rituximab t...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Case Reports in Cardiology |
| Online Access: | http://dx.doi.org/10.1155/2015/523149 |
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| author | Calvin Ke Amit Khosla Margot K. Davis Cameron Hague Mustafa Toma |
| author_facet | Calvin Ke Amit Khosla Margot K. Davis Cameron Hague Mustafa Toma |
| author_sort | Calvin Ke |
| collection | DOAJ |
| description | Coronary artery vasospasm (CAV) can be triggered by medication reactions. CAV occurring after multiple exposures to rituximab has not been previously described. A 61-year-old woman with no cardiac risk factors was treated with the sixth cycle of gemcitabine, cisplatin, dexamethasone, and rituximab therapy. Fifteen minutes after rituximab infusion commenced, she developed typical cardiac chest pain with ST segment elevations on electrocardiogram. Angiogram revealed evidence of coronary vasospasm. The patient was successfully treated with amlodipine. This case underlines the importance of monitoring cardiac side effects of rituximab therapy, even after multiple cycles. |
| format | Article |
| id | doaj-art-cafd0bff045446d29425277a7f1aeef7 |
| institution | Kabale University |
| issn | 2090-6404 2090-6412 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Cardiology |
| spelling | doaj-art-cafd0bff045446d29425277a7f1aeef72025-02-03T06:42:15ZengWileyCase Reports in Cardiology2090-64042090-64122015-01-01201510.1155/2015/523149523149A Case of Coronary Vasospasm after Repeat Rituximab InfusionCalvin Ke0Amit Khosla1Margot K. Davis2Cameron Hague3Mustafa Toma4Department of Medicine, St. Paul’s Hospital, University of British Columbia, 548-1081 Burrard Street, Vancouver, BC, V6Z 1Y6, CanadaDivision of Cardiology, St. Paul’s Hospital, University of British Columbia, 479-1081 Burrard Street, Vancouver, BC, V6Z 1Y6, CanadaDivision of Cardiology, St. Paul’s Hospital, University of British Columbia, 479-1081 Burrard Street, Vancouver, BC, V6Z 1Y6, CanadaDepartment of Radiology, St. Paul’s Hospital, University of British Columbia, 2nd Floor, 1081 Burrard Street, Vancouver, BC, V6Z 1Y6, CanadaDivision of Cardiology, St. Paul’s Hospital, University of British Columbia, 479-1081 Burrard Street, Vancouver, BC, V6Z 1Y6, CanadaCoronary artery vasospasm (CAV) can be triggered by medication reactions. CAV occurring after multiple exposures to rituximab has not been previously described. A 61-year-old woman with no cardiac risk factors was treated with the sixth cycle of gemcitabine, cisplatin, dexamethasone, and rituximab therapy. Fifteen minutes after rituximab infusion commenced, she developed typical cardiac chest pain with ST segment elevations on electrocardiogram. Angiogram revealed evidence of coronary vasospasm. The patient was successfully treated with amlodipine. This case underlines the importance of monitoring cardiac side effects of rituximab therapy, even after multiple cycles.http://dx.doi.org/10.1155/2015/523149 |
| spellingShingle | Calvin Ke Amit Khosla Margot K. Davis Cameron Hague Mustafa Toma A Case of Coronary Vasospasm after Repeat Rituximab Infusion Case Reports in Cardiology |
| title | A Case of Coronary Vasospasm after Repeat Rituximab Infusion |
| title_full | A Case of Coronary Vasospasm after Repeat Rituximab Infusion |
| title_fullStr | A Case of Coronary Vasospasm after Repeat Rituximab Infusion |
| title_full_unstemmed | A Case of Coronary Vasospasm after Repeat Rituximab Infusion |
| title_short | A Case of Coronary Vasospasm after Repeat Rituximab Infusion |
| title_sort | case of coronary vasospasm after repeat rituximab infusion |
| url | http://dx.doi.org/10.1155/2015/523149 |
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