Sparstolonin B Suppresses Proliferation and Modulates Toll-like Receptor Signaling and Inflammatory Pathways in Human Colorectal Cancer Cells

Sparstolonin B Suppresses Proliferation and Modulates Toll-like Receptor Signaling and Inflammatory Pathways in Human Colorectal Cancer Cells

<b>Background:</b> Sparstolonin B (SsnB), a natural compound with anti-inflammatory and anti-proliferative properties, was investigated for its effects on cell viability, apoptosis, and inflammatory pathways in human colorectal cancer cells (HCT-116) and healthy human fibroblasts (BJ). P...

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Bibliographic Details
Main Authors: Bürke Çırçırlı, Çağatay Yılmaz, Tuğçe Çeker, Zerrin Barut, Esma Kırımlıoğlu, Mutay Aslan
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Pharmaceuticals
Subjects:
Sparstolonin B
colorectal cancer
apoptosis
toll-like receptor
inflammation
Online Access:https://www.mdpi.com/1424-8247/18/3/300
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