Discovery and validation of CREB1 as a transcription target of icaritin: Implications for the treatment of depressive-like behavior

Depression is a prevalent neuropsychiatric disorder characterized by persistent sadness and a lack of interest, significantly impacting the quality of life. Icaritin, a bioactive compound from Herba Epimedii, which has the antidepressant-like effects. However, the potential target of icaritin in the...

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Bibliographic Details
Main Authors: Ling Gu, Lei Li, Huiying Xu, Yuyan Ling, Ruiting Ma, Meijuan Chen
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Brain Research Bulletin
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0361923025000760
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