Scutellarin prevents obesity-induced renal fibrosis via reduced activation of AP-1

Scutellarin prevents obesity-induced renal fibrosis via reduced activation of AP-1

Abstract Background Renal fibrosis is characterized by the formation of scar tissue in the kidney parenchyma. Obesity, with its rising global incidence, has become a significant cause of renal fibrosis. This study investigates the effect of Scutellarin (SCU) on obesity-induced renal fibrosis. Method...

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Bibliographic Details
Main Authors: Haoan Yi, Yibing Jiang, Wei Li, Ling Shen, Wei Zhang, Shude Li, Yushan Xu, Fei Li
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Journal of Translational Medicine
Subjects:
Renal fibrosis
Obesity
Scutellarin
FOS
JUN
AP-1
Online Access:https://doi.org/10.1186/s12967-025-06616-x
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