The bat influenza A virus subtype H18N11 induces nanoscale MHCII clustering upon host cell attachment

The bat influenza A virus subtype H18N11 induces nanoscale MHCII clustering upon host cell attachment

Abstract Prior to the discovery of bat influenza A virus (IAV) subtypes H17N10 and H18N11, all IAVs were thought to bind sialic acid residues via hemagglutinin (HA) to mediate attachment and subsequent viral entry. However, H17 and H18 engage a proteinaceous receptor: the major histocompatibility co...

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Bibliographic Details
Main Authors: Maria Kaukab Osman, Jonathan Robert, Lukas Broich, Dennis Frank, Robert Grosse, Martin Schwemmle, Antoni G. Wrobel, Kevin Ciminski, Christian Sieben, Peter Reuther
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-58834-y
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https://doi.org/10.1038/s41467-025-58834-y

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