Hmox1 Deficiency Sensitizes Mice to Peroxynitrite Formation and Diabetic Glomerular Microvascular Injuries
Objective. Indirect evidence suggests a role for heme oxygenase-1 (HO-1) in limiting diabetic vasculopathy. The goal of this study was to assess the role of HO-1 in the development of microvascular lesions within glomeruli during diabetes mellitus using a mouse model with specific alteration of the...
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Main Authors: | Olivia Lenoir, François Gaillard, Hélène Lazareth, Blaise Robin, Pierre-Louis Tharaux |
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Format: | Article |
Language: | English |
Published: |
Wiley
2017-01-01
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Series: | Journal of Diabetes Research |
Online Access: | http://dx.doi.org/10.1155/2017/9603924 |
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