Blood Pressure in relation to 24-Hour Urinary Sodium and Potassium Excretion in a Uruguayan Population Sample
Many public health policies in Latin America target an optimized sodium and potassium intake. The aims of this study were to assess the sodium and potassium intake using 24-hour urinary analysis and to study their association with blood pressure in a Uruguayan population cohort using cluster analysi...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | International Journal of Hypertension |
| Online Access: | http://dx.doi.org/10.1155/2018/6956078 |
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| author | Paula Moliterno Ramón Álvarez-Vaz Matias Pécora Leonella Luzardo Luciana Borgarello Alicia Olascoaga Carmen Marino Oscar Noboa Jan A. Staessen José Boggia |
| author_facet | Paula Moliterno Ramón Álvarez-Vaz Matias Pécora Leonella Luzardo Luciana Borgarello Alicia Olascoaga Carmen Marino Oscar Noboa Jan A. Staessen José Boggia |
| author_sort | Paula Moliterno |
| collection | DOAJ |
| description | Many public health policies in Latin America target an optimized sodium and potassium intake. The aims of this study were to assess the sodium and potassium intake using 24-hour urinary analysis and to study their association with blood pressure in a Uruguayan population cohort using cluster analysis. A total of 149 participants (aged 20–85 years) were included in the study, and office blood pressure, anthropometric measurements, biochemical parameters in the blood, and 24-hour urine samples were obtained. The overall mean sodium and potassium excretion was 152.9 ± 57.3 mmol/day (8.9 ± 3.4 g/day of salt) and 55.4 ± 19.6 mmol/day, respectively. The average office systolic/diastolic blood pressure was 124.6 ± 16.7/79.3 ± 9.9 mmHg. Three compact spherical clusters were defined in untreated participants based on predetermined attributes, including blood pressure, age, and sodium and potassium excretion. The major characteristics of the three clusters were (1) high systolic blood pressure and moderate sodium excretion, (2) moderate systolic blood pressure and very high sodium excretion, and (3) low systolic blood pressure and low sodium excretion. Participants in cluster three had systolic blood pressure values that were 23.9 mmHg (95% confidence interval: −29.5 to −1.84) lower than those in cluster one. Participants in cluster two had blood pressure levels similar to those in cluster one (P = 0.32) and worse metabolic profiles than those in cluster one and three (P < 0.05). None of the clusters showed high blood pressure levels and high sodium excretion. No linear association was found between blood pressure and urinary sodium excretion (r < 0.14; P > 0.47). An effect of sodium and potassium intake on blood pressure levels was not found at the population level using regression or cluster analysis. |
| format | Article |
| id | doaj-art-ca3956024b1348db9aa12df8b2e9148e |
| institution | Kabale University |
| issn | 2090-0384 2090-0392 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Hypertension |
| spelling | doaj-art-ca3956024b1348db9aa12df8b2e9148e2025-02-03T01:23:56ZengWileyInternational Journal of Hypertension2090-03842090-03922018-01-01201810.1155/2018/69560786956078Blood Pressure in relation to 24-Hour Urinary Sodium and Potassium Excretion in a Uruguayan Population SamplePaula Moliterno0Ramón Álvarez-Vaz1Matias Pécora2Leonella Luzardo3Luciana Borgarello4Alicia Olascoaga5Carmen Marino6Oscar Noboa7Jan A. Staessen8José Boggia9Departamento de Nutrición Clínica, Escuela de Nutrición, Universidad de la República, Montevideo, UruguayInstituto de Estadística, Universidad de la República, Montevideo, UruguayDepartamento de Fisiopatología, Universidad de la República, Montevideo, UruguayDepartamento de Fisiopatología, Universidad de la República, Montevideo, UruguayLaboratorio de Patología Clínica, Universidad de la República, Montevideo, UruguayLaboratorio de Patología Clínica, Universidad de la República, Montevideo, UruguayÁrea de Investigación, Escuela de Nutrición, Universidad de la República, Montevideo, UruguayCentro de Nefrología, Universidad de la República, Montevideo, UruguayStudies Coordinating Centre, Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven, BelgiumDepartamento de Fisiopatología, Universidad de la República, Montevideo, UruguayMany public health policies in Latin America target an optimized sodium and potassium intake. The aims of this study were to assess the sodium and potassium intake using 24-hour urinary analysis and to study their association with blood pressure in a Uruguayan population cohort using cluster analysis. A total of 149 participants (aged 20–85 years) were included in the study, and office blood pressure, anthropometric measurements, biochemical parameters in the blood, and 24-hour urine samples were obtained. The overall mean sodium and potassium excretion was 152.9 ± 57.3 mmol/day (8.9 ± 3.4 g/day of salt) and 55.4 ± 19.6 mmol/day, respectively. The average office systolic/diastolic blood pressure was 124.6 ± 16.7/79.3 ± 9.9 mmHg. Three compact spherical clusters were defined in untreated participants based on predetermined attributes, including blood pressure, age, and sodium and potassium excretion. The major characteristics of the three clusters were (1) high systolic blood pressure and moderate sodium excretion, (2) moderate systolic blood pressure and very high sodium excretion, and (3) low systolic blood pressure and low sodium excretion. Participants in cluster three had systolic blood pressure values that were 23.9 mmHg (95% confidence interval: −29.5 to −1.84) lower than those in cluster one. Participants in cluster two had blood pressure levels similar to those in cluster one (P = 0.32) and worse metabolic profiles than those in cluster one and three (P < 0.05). None of the clusters showed high blood pressure levels and high sodium excretion. No linear association was found between blood pressure and urinary sodium excretion (r < 0.14; P > 0.47). An effect of sodium and potassium intake on blood pressure levels was not found at the population level using regression or cluster analysis.http://dx.doi.org/10.1155/2018/6956078 |
| spellingShingle | Paula Moliterno Ramón Álvarez-Vaz Matias Pécora Leonella Luzardo Luciana Borgarello Alicia Olascoaga Carmen Marino Oscar Noboa Jan A. Staessen José Boggia Blood Pressure in relation to 24-Hour Urinary Sodium and Potassium Excretion in a Uruguayan Population Sample International Journal of Hypertension |
| title | Blood Pressure in relation to 24-Hour Urinary Sodium and Potassium Excretion in a Uruguayan Population Sample |
| title_full | Blood Pressure in relation to 24-Hour Urinary Sodium and Potassium Excretion in a Uruguayan Population Sample |
| title_fullStr | Blood Pressure in relation to 24-Hour Urinary Sodium and Potassium Excretion in a Uruguayan Population Sample |
| title_full_unstemmed | Blood Pressure in relation to 24-Hour Urinary Sodium and Potassium Excretion in a Uruguayan Population Sample |
| title_short | Blood Pressure in relation to 24-Hour Urinary Sodium and Potassium Excretion in a Uruguayan Population Sample |
| title_sort | blood pressure in relation to 24 hour urinary sodium and potassium excretion in a uruguayan population sample |
| url | http://dx.doi.org/10.1155/2018/6956078 |
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