A Study into the Electrochemical Behavior of Nano Antibiotics as A Promising Treatment for Helicobacter Pylori Infection by Cyclic Voltammetry

The helicobacter-pylori (H.pylori) bacteria that infects the digestive system is one of the bacteria that is intractable in routine treatments with antibiotics, as it has been studied using nano-antibiotics studied by the electrochemical behavior of three Nano antibiotics. The study aims to ident...

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Main Authors: Sarah Abbas Hussein Al-saeed, Muhammed Mizher Radhi, Zuhair Numan Hamed
Format: Article
Language:English
Published: middle technical university 2022-11-01
Series:Journal of Techniques
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Online Access:https://journal.mtu.edu.iq/index.php/MTU/article/view/548
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author Sarah Abbas Hussein Al-saeed
Muhammed Mizher Radhi
Zuhair Numan Hamed
author_facet Sarah Abbas Hussein Al-saeed
Muhammed Mizher Radhi
Zuhair Numan Hamed
author_sort Sarah Abbas Hussein Al-saeed
collection DOAJ
description The helicobacter-pylori (H.pylori) bacteria that infects the digestive system is one of the bacteria that is intractable in routine treatments with antibiotics, as it has been studied using nano-antibiotics studied by the electrochemical behavior of three Nano antibiotics. The study aims to identify the extent of the effect of micro-antibiotics on the composition of the blood serum medium by electrochemical analysis using the cyclic voltammetric method and to compare it with nano-antibiotics. Three Nano-antibiotics such as Amoxicillin NPs, Azithromycin NPs, and Metronidazole NPs, and the mixture of the three nanoparticles as Nano-Kit were investigated in blood serum medium utilizing cyclic voltammetry methods by a glass carbonic electrode (GCE). The three nanoparticles in antibiotics were prepared by converting the micro antibiotic with a lyophilizer technique and characterization by field emission scanning electron microscopy (FESEM) with all antibiotics in Nano size. The results showed that all Nano compounds act as an antioxidant antibiotic in the blood serum medium. The study also included the electrochemical characterization of the Nano-kit of the mixture for the three Nano-biotics to prove anti-oxidative stress. It was found that the three nano-biotics have reduced current peaks without any oxidation peaks. The three nano-antibiotics can be an excellent treatment to eradicate H. pylori infection permanently. Therefore, the results of this research can be adapted to use the nano-kit of the mixture in the appropriate treatment of H.pylori infection.
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institution Kabale University
issn 1818-653X
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publishDate 2022-11-01
publisher middle technical university
record_format Article
series Journal of Techniques
spelling doaj-art-ca3752b064a44a5295869932537520532025-01-19T11:07:09Zengmiddle technical universityJournal of Techniques1818-653X2708-83832022-11-014Special Issue10.51173/jt.v4i33.548A Study into the Electrochemical Behavior of Nano Antibiotics as A Promising Treatment for Helicobacter Pylori Infection by Cyclic VoltammetrySarah Abbas Hussein Al-saeed0Muhammed Mizher Radhi1Zuhair Numan Hamed2College of Health & Medical Technology - Baghdad, Middle Technical University, Baghdad, IraqCollege of Health & Medical Technology - Baghdad, Middle Technical University, Baghdad, IraqCollege of Health & Medical Technology - Baghdad, Middle Technical University, Baghdad, Iraq The helicobacter-pylori (H.pylori) bacteria that infects the digestive system is one of the bacteria that is intractable in routine treatments with antibiotics, as it has been studied using nano-antibiotics studied by the electrochemical behavior of three Nano antibiotics. The study aims to identify the extent of the effect of micro-antibiotics on the composition of the blood serum medium by electrochemical analysis using the cyclic voltammetric method and to compare it with nano-antibiotics. Three Nano-antibiotics such as Amoxicillin NPs, Azithromycin NPs, and Metronidazole NPs, and the mixture of the three nanoparticles as Nano-Kit were investigated in blood serum medium utilizing cyclic voltammetry methods by a glass carbonic electrode (GCE). The three nanoparticles in antibiotics were prepared by converting the micro antibiotic with a lyophilizer technique and characterization by field emission scanning electron microscopy (FESEM) with all antibiotics in Nano size. The results showed that all Nano compounds act as an antioxidant antibiotic in the blood serum medium. The study also included the electrochemical characterization of the Nano-kit of the mixture for the three Nano-biotics to prove anti-oxidative stress. It was found that the three nano-biotics have reduced current peaks without any oxidation peaks. The three nano-antibiotics can be an excellent treatment to eradicate H. pylori infection permanently. Therefore, the results of this research can be adapted to use the nano-kit of the mixture in the appropriate treatment of H.pylori infection. https://journal.mtu.edu.iq/index.php/MTU/article/view/548Amoxicillin NPsAzithromycin NPsCyclic Voltammetry FESEMH-pylori infectionMetronidazole NPsNano-kit
spellingShingle Sarah Abbas Hussein Al-saeed
Muhammed Mizher Radhi
Zuhair Numan Hamed
A Study into the Electrochemical Behavior of Nano Antibiotics as A Promising Treatment for Helicobacter Pylori Infection by Cyclic Voltammetry
Journal of Techniques
Amoxicillin NPs
Azithromycin NPs
Cyclic Voltammetry FESEM
H-pylori infection
Metronidazole NPs
Nano-kit
title A Study into the Electrochemical Behavior of Nano Antibiotics as A Promising Treatment for Helicobacter Pylori Infection by Cyclic Voltammetry
title_full A Study into the Electrochemical Behavior of Nano Antibiotics as A Promising Treatment for Helicobacter Pylori Infection by Cyclic Voltammetry
title_fullStr A Study into the Electrochemical Behavior of Nano Antibiotics as A Promising Treatment for Helicobacter Pylori Infection by Cyclic Voltammetry
title_full_unstemmed A Study into the Electrochemical Behavior of Nano Antibiotics as A Promising Treatment for Helicobacter Pylori Infection by Cyclic Voltammetry
title_short A Study into the Electrochemical Behavior of Nano Antibiotics as A Promising Treatment for Helicobacter Pylori Infection by Cyclic Voltammetry
title_sort study into the electrochemical behavior of nano antibiotics as a promising treatment for helicobacter pylori infection by cyclic voltammetry
topic Amoxicillin NPs
Azithromycin NPs
Cyclic Voltammetry FESEM
H-pylori infection
Metronidazole NPs
Nano-kit
url https://journal.mtu.edu.iq/index.php/MTU/article/view/548
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