Untreated Active Tuberculosis in Pregnancy with Intraocular Dissemination: A Case Report and Review of the Literature

Background. Tuberculosis (TB) is a disease that affects hundreds of millions of people across the world. However, the incidence in developed countries has decreased over the past decades causing physicians to become unfamiliar with its unspecific symptoms. Pregnant individuals are especially difficu...

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Main Authors: Shadi Rezai, Stephen LoBue, Daniel Adams, Yewande Oladipo, Ramses Posso, Tiffany Mapp, Crystal Santiago, Manisha Jain, William D. Marino, Cassandra E. Henderson
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Case Reports in Pulmonology
Online Access:http://dx.doi.org/10.1155/2015/370462
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author Shadi Rezai
Stephen LoBue
Daniel Adams
Yewande Oladipo
Ramses Posso
Tiffany Mapp
Crystal Santiago
Manisha Jain
William D. Marino
Cassandra E. Henderson
author_facet Shadi Rezai
Stephen LoBue
Daniel Adams
Yewande Oladipo
Ramses Posso
Tiffany Mapp
Crystal Santiago
Manisha Jain
William D. Marino
Cassandra E. Henderson
author_sort Shadi Rezai
collection DOAJ
description Background. Tuberculosis (TB) is a disease that affects hundreds of millions of people across the world. However, the incidence in developed countries has decreased over the past decades causing physicians to become unfamiliar with its unspecific symptoms. Pregnant individuals are especially difficult because many symptoms of active TB can mimic normal physiological changes of pregnancy. We present a case report of a 26-year-old multiparous woman, G4P3003, at 38-week gestation with a history of positive PPD who emigrated from Ghana 6 years ago. She came to the hospital with an initial complaint of suprapubic pain, pressure, and possible leakage of amniotic fluid for the past week. Patient also complained of a productive cough for the past 3 to 4 months with a decrease in vision occurring with the start of pregnancy. Visual acuity was worse than 20/200 in both eyes. Definitive diagnosis of active TB was delayed due to patient refusal of chest X-ray. Fortunately, delay in diagnosis was minimized since patient delivered within 24 hours of admission. Active TB was confirmed with intraocular dissemination. Patient had optic atrophy OS (left eye) and papillitis, choroiditis, and uveitis OD (right eye) due to TB infiltration. Fetus was asymptomatic and anti-TB therapy was started for both patients.
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spelling doaj-art-ca3033cc10cc484eb12bbd9090a7d1f02025-02-03T05:46:18ZengWileyCase Reports in Pulmonology2090-68462090-68542015-01-01201510.1155/2015/370462370462Untreated Active Tuberculosis in Pregnancy with Intraocular Dissemination: A Case Report and Review of the LiteratureShadi Rezai0Stephen LoBue1Daniel Adams2Yewande Oladipo3Ramses Posso4Tiffany Mapp5Crystal Santiago6Manisha Jain7William D. Marino8Cassandra E. Henderson9Department of Obstetrics and Gynecology, Lincoln Medical and Mental Health Center, Bronx, NY 10451, USASt. George’s University, School of Medicine, GrenadaSt. George’s University, School of Medicine, GrenadaSt. George’s University, School of Medicine, GrenadaDepartment of Obstetrics and Gynecology, Lincoln Medical and Mental Health Center, Bronx, NY 10451, USADepartment of Obstetrics and Gynecology, Lincoln Medical and Mental Health Center, Bronx, NY 10451, USADepartment of Obstetrics and Gynecology, Lincoln Medical and Mental Health Center, Bronx, NY 10451, USADepartment of Obstetrics and Gynecology, Lincoln Medical and Mental Health Center, Bronx, NY 10451, USAConey Island Hospital, Pulmonary Medicine, Brooklyn, NY 11235, USADepartment of Obstetrics and Gynecology, Lincoln Medical and Mental Health Center, Bronx, NY 10451, USABackground. Tuberculosis (TB) is a disease that affects hundreds of millions of people across the world. However, the incidence in developed countries has decreased over the past decades causing physicians to become unfamiliar with its unspecific symptoms. Pregnant individuals are especially difficult because many symptoms of active TB can mimic normal physiological changes of pregnancy. We present a case report of a 26-year-old multiparous woman, G4P3003, at 38-week gestation with a history of positive PPD who emigrated from Ghana 6 years ago. She came to the hospital with an initial complaint of suprapubic pain, pressure, and possible leakage of amniotic fluid for the past week. Patient also complained of a productive cough for the past 3 to 4 months with a decrease in vision occurring with the start of pregnancy. Visual acuity was worse than 20/200 in both eyes. Definitive diagnosis of active TB was delayed due to patient refusal of chest X-ray. Fortunately, delay in diagnosis was minimized since patient delivered within 24 hours of admission. Active TB was confirmed with intraocular dissemination. Patient had optic atrophy OS (left eye) and papillitis, choroiditis, and uveitis OD (right eye) due to TB infiltration. Fetus was asymptomatic and anti-TB therapy was started for both patients.http://dx.doi.org/10.1155/2015/370462
spellingShingle Shadi Rezai
Stephen LoBue
Daniel Adams
Yewande Oladipo
Ramses Posso
Tiffany Mapp
Crystal Santiago
Manisha Jain
William D. Marino
Cassandra E. Henderson
Untreated Active Tuberculosis in Pregnancy with Intraocular Dissemination: A Case Report and Review of the Literature
Case Reports in Pulmonology
title Untreated Active Tuberculosis in Pregnancy with Intraocular Dissemination: A Case Report and Review of the Literature
title_full Untreated Active Tuberculosis in Pregnancy with Intraocular Dissemination: A Case Report and Review of the Literature
title_fullStr Untreated Active Tuberculosis in Pregnancy with Intraocular Dissemination: A Case Report and Review of the Literature
title_full_unstemmed Untreated Active Tuberculosis in Pregnancy with Intraocular Dissemination: A Case Report and Review of the Literature
title_short Untreated Active Tuberculosis in Pregnancy with Intraocular Dissemination: A Case Report and Review of the Literature
title_sort untreated active tuberculosis in pregnancy with intraocular dissemination a case report and review of the literature
url http://dx.doi.org/10.1155/2015/370462
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