Multimodality Image Analysis in a Cohort of Patients with Atypical Juvenile Ocular Toxocariasis
Purpose. To analysis the multimodal imaging of a group of patients diagnosed clinically with atypical juvenile ocular toxocariasis (OT). Methods. In this case series study, we examined 9 young patients diagnosed with atypical OT. Routine ophthalmological examinations, fundus photography, optical-coh...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2021-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2021/4853531 |
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| Summary: | Purpose. To analysis the multimodal imaging of a group of patients diagnosed clinically with atypical juvenile ocular toxocariasis (OT). Methods. In this case series study, we examined 9 young patients diagnosed with atypical OT. Routine ophthalmological examinations, fundus photography, optical-coherence tomography (OCT), fluorescein angiography (FFA), and B-mode ultrasound were performed. A questionnaire was used to record whether the patients were newly diagnosed and whether they had a history of exposure to a cat and dog. Aqueous humor and serum samples were taken for serological tests. Results. In all the patients, yellow-and-white dot-shaped lesions and perivascular white sheath were seen in the fundus. Heterogeneous changes including hyper-reflection in the disrupted neuroretina, hyper-reflection in the outer retinal layer, high-reflection mass on the surface of the neuroretina accompanied with reflective attenuation, and high-reflection mass involving the entire neuroretina or high-reflection mass in the vitreous body were noticed in OCT images. On FFA, seven of these patients (77.8%) showed leakage of fluorescein in the small- and medium-branch veins of the retina, and a “bristle-like” change indicated increased permeability of the vessels. B-mode ultrasound showed proliferative membranes and proliferative bands (33.3%), as well as spotted opacity in the vitreous (66.7%). The antibodies to Toxocara canis in the aqueous humor and serum were positive, and the Goldmann–Witmer coefficient was significantly increased in 6 out of 7 patients. Conclusions. Multimodality images are useful in the diagnosis of atypical juvenile OT, which could be easily overlooked and misdiagnosed. |
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| ISSN: | 2090-004X 2090-0058 |